{"id":"W2022513417","doi":"10.1016/s0896-6273(03)00228-9","title":"Activation of PI3-Kinase Is Required for AMPA Receptor Insertion during LTP of mEPSCs in Cultured Hippocampal Neurons","year":2003,"lang":"en","type":"article","venue":"Neuron","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":347,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health; Vancouver Hospital and Health Sciences Centre; Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto; SickKids Foundation; University of British Columbia; Hospital for Sick Children","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Canadian Institutes of Health Research; Heart and Stroke Foundation of British Columbia and Yukon; EJLB Foundation","keywords":"Long-term potentiation; AMPA receptor; Synaptic plasticity; NMDA receptor; Neuroscience; Postsynaptic potential; LTP induction; Silent synapse; Hippocampal formation; Long-term depression; Chemistry; Glutamate receptor; Cell biology; Biology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003430878,0.0003329974,0.0005656462,0.00029636,0.0004804318,0.0008452854,0.0005069872,0.0003720559,0.001359812],"category_scores_gemma":[0.0006311418,0.0003892638,0.0006631804,0.0002948137,0.0003895708,0.0009258859,0.0005422819,0.00156294,0.0006612953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00139859,"about_ca_system_score_gemma":0.0005890089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002404602,"about_ca_topic_score_gemma":0.004781106,"domain_scores_codex":[0.9996044,0.00003634635,0.00006836747,0.00005576096,0.00009244175,0.0001426433],"domain_scores_gemma":[0.9996452,0.00008786488,0.00008458138,0.00006286622,0.00005080648,0.00006867859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005298759,0.00003493163,0.0002071545,0.00003633666,0.000009196631,0.000131203,0.00002398031,0.00003958793,0.9980941,0.0001612304,0.00003945176,0.0006929612],"study_design_scores_gemma":[0.00003610735,0.00008591676,0.007990715,0.00000884475,0.00001769975,0.0002168029,0.00005426604,0.0008711551,0.9899887,0.0001482652,0.0005745748,0.000006903562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931769,0.001337364,0.002697356,0.0002652359,0.00005888964,0.00003167208,0.0007040814,0.00008111192,0.001647316],"genre_scores_gemma":[0.9957637,0.0004114179,0.001461086,0.00006499652,0.00001323432,0.00005068818,0.0007932603,0.00004137419,0.001400387],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002404602,"threshold_uncertainty_score":0.01014757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06951304173521192,"score_gpt":0.3447272776689449,"score_spread":0.275214235933733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}