{"id":"W2022529094","doi":"10.1016/j.biochi.2007.05.002","title":"Specific subcellular localization of siRNAs delivered by lipoplex in MCF-7 breast cancer cells","year":2007,"lang":"en","type":"article","venue":"Biochimie","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Moncton","funders":"Atlantic Canada Opportunities Agency","keywords":"MCF-7; Small interfering RNA; Cyclin D1; Cell biology; Biology; Cytoplasm; Transfection; Subcellular localization; Chemistry; Molecular biology; Cancer cell; Cell cycle; Cancer research; Cell; Cell culture; Cancer; Biochemistry; Human breast; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001517786,0.0001396199,0.0001396643,0.00006754517,0.00002585675,0.000009564431,0.0001734229,0.0001638395,0.0001095202],"category_scores_gemma":[0.000004896081,0.0001397579,0.00006824354,0.0001443642,0.0000650894,0.000004204159,0.00005209943,0.00005746087,0.00001556561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002701507,"about_ca_system_score_gemma":0.00003853887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003391241,"about_ca_topic_score_gemma":0.0002573355,"domain_scores_codex":[0.9990317,0.00002541115,0.0002891404,0.0002894828,0.0001233411,0.0002409198],"domain_scores_gemma":[0.9995025,0.000006049746,0.00009340339,0.000238907,0.00009572407,0.00006336919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001768702,0.00009840284,0.004708985,0.00001613261,0.00001839952,0.00000404241,0.00003703346,0.0001683053,0.9792326,0.000008816833,0.01225072,0.003279673],"study_design_scores_gemma":[0.0004222092,0.0001012647,0.003394716,0.00002977262,0.000007210094,0.000004405217,0.00006183662,0.0000927588,0.9854933,0.000009474468,0.01021631,0.0001667463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889458,0.003576425,0.006529025,0.00004122534,0.0002088944,0.0001255238,0.0001324614,0.000006245936,0.0004343972],"genre_scores_gemma":[0.9970143,0.002018702,0.00009658889,0.0001486045,0.0001557674,0.000004324586,0.0001925653,0.00001779831,0.0003513015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008068545,"threshold_uncertainty_score":0.5699161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007466776886515576,"score_gpt":0.2308772637315927,"score_spread":0.2234104868450771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}