{"id":"W2022596095","doi":"10.1007/s11306-014-0653-y","title":"De novo synthesize of bile acids in pulmonary arterial hypertension lung","year":2014,"lang":"en","type":"article","venue":"Metabolomics","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"MaRS; University Health Network; Discovery Centre; University of Toronto","funders":"","keywords":"Lung; Bile acid; Cytochrome P450; Pathogenesis; Chemistry; Biology; Isozyme; Metabolomics; Biochemistry; Metabolism; Medicine; Pathology; Internal medicine; Bioinformatics; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001192995,0.0001675621,0.0002479872,0.0006311249,0.0001688161,0.0003682765,0.00007644833,0.0001904064,0.0003607929],"category_scores_gemma":[0.0001180233,0.0001442428,0.0001447329,0.0002510403,0.0001678903,0.0002506973,0.0002459534,0.000246606,0.0001347365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001317776,"about_ca_system_score_gemma":0.0001088062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002749982,"about_ca_topic_score_gemma":0.0005070872,"domain_scores_codex":[0.9999003,0.00001940281,0.000007082551,0.00002904563,0.0000292534,0.00001498581],"domain_scores_gemma":[0.999891,0.00002062006,0.00003893711,0.00000773279,0.00001845068,0.00002319298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001828197,0.00001251507,0.006286103,0.00004608817,0.00001661671,0.0001722778,0.00003221483,0.00004060345,0.9885766,0.0001165722,0.00003230571,0.004485396],"study_design_scores_gemma":[0.00002229266,0.0004651358,0.3308442,0.00002272784,0.0001206814,0.002818355,0.0002613265,0.00223933,0.6569198,0.001703806,0.004556979,0.00002533438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832356,0.01010624,0.005129399,0.0003047463,0.00002112751,0.00001363195,0.0003900068,0.00005381307,0.0007454538],"genre_scores_gemma":[0.9926984,0.003111741,0.00283748,0.00008594045,0.00003100818,0.00001277621,0.0003232431,0.000008765875,0.0008907306],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006311249,"threshold_uncertainty_score":0.001206934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01936570666585975,"score_gpt":0.2666214080372701,"score_spread":0.2472557013714103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}