{"id":"W2022645386","doi":"10.1006/nbdi.2000.0323","title":"PMP22 Carrying the Trembler or Trembler-J Mutation Is Intracellularly Retained in Myelinating Schwann Cells","year":2000,"lang":"en","type":"article","venue":"Neurobiology of Disease","topic":"Hereditary Neurological Disorders","field":"Neuroscience","cited_by":95,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Endoplasmic reticulum; Biology; Myelin; Mutant; Cell biology; Molecular biology; Epitope; Cytoplasm; Peripheral myelin protein 22; Gene; Phenotype; Genetics; Neuroscience; Central nervous system; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008001205,0.0003464668,0.000263691,0.0003110823,0.0002715758,0.0003738564,0.0002078682,0.0004415529,0.001558073],"category_scores_gemma":[0.0002497351,0.0001525864,0.0001429838,0.0001756662,0.0002844078,0.0002225786,0.0002997723,0.0003296514,0.0008494229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001648492,"about_ca_system_score_gemma":0.0001046128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005496044,"about_ca_topic_score_gemma":0.0004424268,"domain_scores_codex":[0.9998944,0.00001462679,0.000009720756,0.00002329796,0.00003047185,0.00002743865],"domain_scores_gemma":[0.9998134,0.00002178558,0.00005974423,0.00001934319,0.00002233392,0.00006351315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001524311,0.00001823167,0.001238095,0.00002274367,0.00001099611,0.002891455,0.00003606868,0.00003950997,0.9945102,0.000110878,0.00005487101,0.0009144424],"study_design_scores_gemma":[0.0001025978,0.0007581681,0.07673049,0.00002606497,0.00009546134,0.06498027,0.0003953374,0.001491266,0.8485321,0.0004564986,0.006386029,0.00004567483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985064,0.0002523816,0.0004312895,0.0000270895,0.00001592482,0.00000246724,0.00006037383,0.00003108087,0.0006729278],"genre_scores_gemma":[0.9983815,0.0001325153,0.0002645766,0.0000176885,0.000009502353,0.000006287624,0.0001905638,0.00001484661,0.0009824937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001558073,"threshold_uncertainty_score":0.005212247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03399166585262556,"score_gpt":0.2619496527639774,"score_spread":0.2279579869113519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}