{"id":"W2022671309","doi":"10.1097/mnh.0b013e32832923c3","title":"Molecular mechanisms of hypertension: role of Nox family NADPH oxidases","year":2009,"lang":"en","type":"review","venue":"Current Opinion in Nephrology & Hypertension","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"NOX1; NOX4; NADPH oxidase; Oxidative stress; Reactive oxygen species; Endothelial dysfunction; Peroxynitrite; Angiotensin II; Cell biology; Chemistry; Biology; Medicine; Internal medicine; Superoxide; Receptor; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004785757,0.0008423514,0.001112626,0.000595011,0.0002253278,0.001080132,0.0007571775,0.0009774915,0.0039515],"category_scores_gemma":[0.0005568844,0.0001318768,0.0004931998,0.0006341672,0.0003237888,0.001306463,0.0004714697,0.001673125,0.001918201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004312587,"about_ca_system_score_gemma":0.0007421146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002765863,"about_ca_topic_score_gemma":0.0002950795,"domain_scores_codex":[0.9998069,0.00003600702,0.00002701243,0.0000381826,0.00006658339,0.00002517764],"domain_scores_gemma":[0.9996876,0.00007022004,0.000060577,0.000007589059,0.0001341839,0.00003995778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004272118,0.00009575696,0.0007803387,0.02958926,0.0003018348,0.001297371,0.0001717466,0.0004429535,0.01485382,0.006088421,0.2500581,0.6958932],"study_design_scores_gemma":[0.00002219337,0.0001443087,0.001565092,0.001723389,0.000194511,0.002378806,0.00008557584,0.0001485476,0.002215347,0.002296822,0.9892026,0.00002284042],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004752018,0.9892358,0.0004600761,0.002445149,0.00621517,0.00001113597,0.00005062872,0.0000318376,0.00107497],"genre_scores_gemma":[0.002664341,0.9842717,0.0003072692,0.001276036,0.009530352,0.00001037951,0.0001050218,0.000007499345,0.001827507],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0039515,"threshold_uncertainty_score":0.01321906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07157229051669217,"score_gpt":0.3046755349117694,"score_spread":0.2331032443950772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}