{"id":"W2022674028","doi":"10.1097/mpa.0b013e318073d1c9","title":"Activation of Exchange Protein Directly Activated by Cyclic Adenosine Monophosphate and Protein Kinase A Regulate Common and Distinct Steps in Promoting Plasma Membrane Exocytic and Granule-to-Granule Fusions in Rat Islet β Cells","year":2007,"lang":"en","type":"article","venue":"Pancreas","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Exocytosis; Forskolin; Protein kinase A; Cyclic adenosine monophosphate; Cell biology; Granule (geology); Biology; Adenosine; Chemistry; Secretion; Kinase; Biochemistry; Endocrinology; Stimulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001319403,0.0002736533,0.0002262313,0.0001775446,0.0001063621,0.0002127926,0.0001517885,0.0002017742,0.000608088],"category_scores_gemma":[0.00008252533,0.0001264718,0.0003871462,0.000110658,0.000192071,0.000285757,0.0002297828,0.0004250524,0.0001426602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002351739,"about_ca_system_score_gemma":0.0001413008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002981253,"about_ca_topic_score_gemma":0.0004429933,"domain_scores_codex":[0.9998875,0.00001195513,0.000009425991,0.00003344543,0.00002502926,0.00003266512],"domain_scores_gemma":[0.9999341,0.000007930608,0.00001944763,0.000008739184,0.00000675704,0.00002296676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001985451,0.00001310503,0.0002038282,0.00002120515,0.000003018626,0.00004532963,0.00000918586,0.00002038828,0.9989096,0.0000446077,0.000006300111,0.0005249821],"study_design_scores_gemma":[0.00002424246,0.0002689849,0.01293041,0.000004626199,0.00001736294,0.0002211772,0.00004116611,0.0006376087,0.9852718,0.00004362112,0.0005343051,0.000004772491],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975199,0.0008544828,0.001087635,0.0000286709,0.000009200978,0.00001164136,0.00009313801,0.00002055693,0.0003747281],"genre_scores_gemma":[0.9969314,0.0005920278,0.001461058,0.00002238568,0.000008502499,0.00003530956,0.0001593818,0.000007815021,0.0007819617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000608088,"threshold_uncertainty_score":0.002034247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00933524647957268,"score_gpt":0.233098889160587,"score_spread":0.2237636426810144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}