{"id":"W2022676280","doi":"10.1016/s0198-8859(01)00339-1","title":"Two-step high resolution sequence-based HLA-DRB typing of exon 2 DNA with taxonomy-based sequence analysis allele assignment","year":2001,"lang":"en","type":"article","venue":"Human Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Centre for Disease Control; University of British Columbia; University of Manitoba","funders":"","keywords":"Biology; Genetics; Polymerase chain reaction; Allele; Primer (cosmetics); Typing; Sequence analysis; Exon; DNA sequencing; Molecular biology; DNA; Gene; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005384822,0.0003568014,0.000547143,0.001007854,0.0003986943,0.0005896262,0.0004455717,0.0005117747,0.001264571],"category_scores_gemma":[0.001266436,0.0004038535,0.0004542953,0.0006487868,0.00029708,0.000339628,0.0006600869,0.0007896176,0.001474064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001760809,"about_ca_system_score_gemma":0.0003812379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009315552,"about_ca_topic_score_gemma":0.001759376,"domain_scores_codex":[0.9993916,0.0001599736,0.00004847142,0.0001276335,0.000164848,0.0001074438],"domain_scores_gemma":[0.9990338,0.0003291604,0.00008577184,0.0001783645,0.0002487656,0.0001241692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000303471,0.0000544992,0.0039417,0.00005818614,0.00001976614,0.00004959985,0.00008489148,0.0001845533,0.9786469,0.0001387615,0.0001295451,0.01638819],"study_design_scores_gemma":[0.0001081049,0.0009047388,0.08785579,0.00002927557,0.0002197834,0.002473112,0.0002963401,0.02187032,0.8794487,0.0009209358,0.005798827,0.00007414632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.809438,0.0005469559,0.1860353,0.0001558873,0.00004622474,0.0002299683,0.0009436544,0.0005347793,0.00206929],"genre_scores_gemma":[0.6746992,0.0002861899,0.3185929,0.0001476546,0.00001912929,0.0002144672,0.002543538,0.0001030538,0.003393763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001264571,"threshold_uncertainty_score":0.00423044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04110227879421597,"score_gpt":0.2508683638432231,"score_spread":0.2097660850490071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}