{"id":"W2022720324","doi":"10.1016/j.metabol.2003.09.009","title":"Cyclooxygenase inhibition is associated with downregulation of apolipoprotein AI promoter activity in cultured hepatoma cell line HepG2","year":2004,"lang":"en","type":"article","venue":"Metabolism","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Molecular biology; Transfection; Chloramphenicol acetyltransferase; Reporter gene; Cell culture; Gene expression; Apolipoprotein B; Hep G2; Biology; Cyclooxygenase; Promoter; Western blot; Transcription (linguistics); Gene; Chemistry; Enzyme; Endocrinology; Biochemistry; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001361696,0.0004199719,0.0003819437,0.0003684192,0.0002878505,0.0004129081,0.0001735144,0.0001846408,0.002962586],"category_scores_gemma":[0.0001634288,0.0002124504,0.0003832947,0.0003637289,0.0002940334,0.0001579975,0.000177002,0.0006561752,0.0009830793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002989686,"about_ca_system_score_gemma":0.0003316955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002882132,"about_ca_topic_score_gemma":0.002906655,"domain_scores_codex":[0.9997911,0.00003410068,0.00002362432,0.00003233167,0.00005256739,0.00006628677],"domain_scores_gemma":[0.9997935,0.00006549368,0.00002420905,0.00004905651,0.0000277061,0.00004017018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002237915,0.00005491972,0.0001910685,0.0000232736,0.000004451852,0.0000668831,0.00001857601,0.00001806403,0.9988134,0.00004787009,0.00006470901,0.0004730792],"study_design_scores_gemma":[0.00001805989,0.0002326989,0.004650267,0.000002947164,0.0000146567,0.0001460078,0.00004593025,0.0002608842,0.9932201,0.00002403145,0.001379594,0.000004755345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919034,0.001758381,0.001866501,0.0001746735,0.0001334505,0.00002733027,0.001068832,0.0001862243,0.002881275],"genre_scores_gemma":[0.9850375,0.001170984,0.001047607,0.00007344356,0.00004240404,0.00007483741,0.00274405,0.00004272281,0.009766357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002962586,"threshold_uncertainty_score":0.009910822,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006042168256898617,"score_gpt":0.2218358845689589,"score_spread":0.2157937163120603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}