{"id":"W2022768816","doi":"10.1006/geno.2002.6802","title":"A Novel Gene Encoding a TIG Multiple Domain Protein Is a Positional Candidate for Autosomal Recessive Polycystic Kidney Disease","year":2002,"lang":"en","type":"article","venue":"Genomics","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; Hospital for Sick Children; University of Alberta","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Autosomal Recessive Polycystic Kidney Disease; Biology; Genetics; Polycystic kidney disease; Positional cloning; PKD1; Molecular biology; Chromosomal region; Gene; Disease gene identification; Nephronophthisis; Locus (genetics); Kidney","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006020808,0.0002240502,0.0001554269,0.00004704981,0.0002077303,0.00004702839,0.0002074041,0.0001093592,0.0001083221],"category_scores_gemma":[0.0001833889,0.000233731,0.0001652326,0.00005966827,0.00007445763,0.000004795113,0.00009831164,0.00005378915,0.0000250001],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004772006,"about_ca_system_score_gemma":0.0002934716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001725186,"about_ca_topic_score_gemma":0.000004525787,"domain_scores_codex":[0.9987371,0.00002379386,0.0002345287,0.0004868132,0.000124278,0.0003934636],"domain_scores_gemma":[0.998902,0.00001202351,0.000106605,0.0003239527,0.00007555848,0.0005798825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004584891,0.0001693322,0.0003257695,0.00005049922,0.0000834178,0.000007242193,0.0001143474,0.00004530307,0.9920922,0.00002799699,0.006402042,0.0002233486],"study_design_scores_gemma":[0.01009287,0.0007466064,0.006345274,0.0001435157,0.0003192129,0.0001055723,0.0001820091,0.01527554,0.8145993,0.001536748,0.1489785,0.001674902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9715071,0.0009817204,0.02044841,0.00104869,0.0001522196,0.0009175554,0.004730316,0.00002286593,0.0001911191],"genre_scores_gemma":[0.9743739,0.00005329321,0.02042454,0.002266721,0.0005056459,0.0003395385,0.001051107,0.00004809194,0.0009371762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1774929,"threshold_uncertainty_score":0.9531271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01138919530383308,"score_gpt":0.2223392232307797,"score_spread":0.2109500279269466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}