{"id":"W2022768816","doi":"10.1006/geno.2002.6802","title":"A Novel Gene Encoding a TIG Multiple Domain Protein Is a Positional Candidate for Autosomal Recessive Polycystic Kidney Disease","year":2002,"lang":"en","type":"article","venue":"Genomics","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; Hospital for Sick Children; University of Alberta","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Autosomal Recessive Polycystic Kidney Disease; Biology; Genetics; Polycystic kidney disease; Positional cloning; PKD1; Molecular biology; Chromosomal region; Gene; Disease gene identification; Nephronophthisis; Locus (genetics); Kidney","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009263863,0.0006448372,0.0004343582,0.0007079068,0.0005589105,0.0002900859,0.0006606694,0.0008778487,0.002673696],"category_scores_gemma":[0.0004241341,0.0001791166,0.0004614237,0.0003678553,0.0004646037,0.0002008607,0.0003604374,0.0008276906,0.0005122957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003186946,"about_ca_system_score_gemma":0.0003046513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001020442,"about_ca_topic_score_gemma":0.0009274786,"domain_scores_codex":[0.9999211,0.000006816445,0.000008433152,0.0000240147,0.00002475318,0.00001486254],"domain_scores_gemma":[0.9997497,0.00008448381,0.00004572518,0.00001587864,0.00001459676,0.00008964783],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006146827,0.00009407723,0.005630129,0.0001029405,0.00005146548,0.1372254,0.0001971997,0.0003425126,0.8459756,0.002547492,0.0005405846,0.006677958],"study_design_scores_gemma":[0.0004844105,0.000915968,0.1160803,0.00005679485,0.0004580574,0.3935921,0.0006084173,0.0123507,0.4551087,0.003344901,0.01687894,0.000120647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885762,0.0004086322,0.007351233,0.0006002192,0.0001723338,0.00003531882,0.0004335397,0.0002299574,0.002192603],"genre_scores_gemma":[0.9925005,0.0001789056,0.004451556,0.0001442681,0.00005776111,0.00002700855,0.0004936397,0.00004915792,0.002097274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002673696,"threshold_uncertainty_score":0.008944392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01138919530383308,"score_gpt":0.2223392232307797,"score_spread":0.2109500279269466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}