{"id":"W2022802975","doi":"10.1016/j.mce.2011.07.010","title":"Transgenic mice expressing the human growth hormone gene provide a model system to study human growth hormone synthesis and secretion in non-tumor-derived pituitary cells: Differential effects of dexamethasone and thyroid hormone","year":2011,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Health Canada; National Institutes of Health; Manitoba Health Research Council","keywords":"Endocrinology; Internal medicine; Somatotropic cell; Hormone; Biology; Pituitary gland; Transgene; Growth hormone–releasing hormone; Thyroid; Pituitary tumors; Anterior pituitary; Endocrine gland; Triiodothyronine; Gene; Growth hormone; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002025742,0.0005575391,0.0003980334,0.000550587,0.0002915424,0.0004449187,0.0003566237,0.0004133606,0.001904803],"category_scores_gemma":[0.0001475682,0.000311055,0.0003634333,0.0003077912,0.0006081451,0.0004153639,0.0002452084,0.001315881,0.0006074926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003312177,"about_ca_system_score_gemma":0.0003319235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009110555,"about_ca_topic_score_gemma":0.002130625,"domain_scores_codex":[0.9998436,0.00002501872,0.00001519205,0.00004408679,0.00004259815,0.00002957074],"domain_scores_gemma":[0.9997991,0.00006025641,0.00004667449,0.00002545878,0.00001205902,0.00005643937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002305718,0.0000385154,0.0002037896,0.00001583892,0.000004530778,0.0001029182,0.00002856269,0.00002100913,0.9981775,0.0003068238,0.00007129381,0.0007985857],"study_design_scores_gemma":[0.0001010674,0.0004311312,0.002686219,0.000007452824,0.00004716588,0.0007715005,0.00007706292,0.000399553,0.9893849,0.0002977989,0.005784426,0.00001163642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9785336,0.002150383,0.01353714,0.0003577934,0.0002025626,0.0001309297,0.002501652,0.0003906902,0.002195372],"genre_scores_gemma":[0.9715225,0.002121989,0.01315389,0.0001559927,0.00005548611,0.0001860324,0.002788993,0.0002735908,0.009741517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001904803,"threshold_uncertainty_score":0.006372213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01303007289111249,"score_gpt":0.2186864819056012,"score_spread":0.2056564090144888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}