{"id":"W2022849751","doi":"10.1016/s0140-6736(10)60876-8","title":"Genes, the environment, and breast cancer","year":2010,"lang":"en","type":"letter","venue":"The Lancet","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women's College Hospital","funders":"","keywords":"Breast cancer; Gene–environment interaction; Penetrance; Odds ratio; Genotype; Risk factors for breast cancer; Oncology; Medicine; Cancer; Demography; Genetics; Bioinformatics; Gynecology; Gene; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002215775,0.001156782,0.001819985,0.0006437392,0.002142925,0.0021596,0.001495568,0.03783196,0.006782414],"category_scores_gemma":[0.01171173,0.0008545439,0.0008448734,0.0005433368,0.002215858,0.002819745,0.001049638,0.02940105,0.005092147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003239104,"about_ca_system_score_gemma":0.00186169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00639534,"about_ca_topic_score_gemma":0.01784925,"domain_scores_codex":[0.9986646,0.0005208908,0.0001169732,0.00014932,0.0003942249,0.0001539643],"domain_scores_gemma":[0.9960611,0.002668684,0.0001928776,0.0001253056,0.0004082627,0.0005438394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002446086,0.00006109456,0.000612962,0.00009350343,0.00003082399,0.0009049118,0.00004573136,0.00007494183,0.0002109465,0.002122476,0.9836829,0.01191503],"study_design_scores_gemma":[0.0008752416,0.0002090871,0.003620082,0.0005793806,0.0001556666,0.002197996,0.0004060154,0.0009061606,0.0004746357,0.02069706,0.9697823,0.00009638498],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0003694691,0.008690516,0.00009124339,0.9594299,0.02870567,0.00000911017,0.00007431035,0.0000280772,0.002601817],"genre_scores_gemma":[0.006334024,0.007989996,0.0002539011,0.8597121,0.1142803,0.0000465805,0.00004320545,0.00002214578,0.01131773],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03783196,"threshold_uncertainty_score":0.02350152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01467923092074592,"score_gpt":0.252643219234115,"score_spread":0.2379639883133691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}