{"id":"W2022867508","doi":"10.1371/journal.pone.0077078","title":"Marine Sediment-Derived Streptomyces Bacteria from British Columbia, Canada Are a Promising Microbiota Resource for the Discovery of Antimicrobial Natural Products","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; University of British Columbia","keywords":"Streptomyces; Antimicrobial; Biology; Secondary metabolite; Novobiocin; Microbiology; Bacteria; Antibiotics; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001025097,0.0007053239,0.0003549116,0.001130542,0.001534079,0.0008051759,0.0002969845,0.0002124036,0.001074661],"category_scores_gemma":[0.0002391169,0.0001805163,0.0001920388,0.001964955,0.0002925285,0.0001510272,0.0004219317,0.0003560453,0.0002816058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001841974,"about_ca_system_score_gemma":0.006088855,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.7584339,"about_ca_topic_score_gemma":0.8888136,"domain_scores_codex":[0.9997219,0.0000103408,0.00001862283,0.00005361403,0.0001257211,0.00006979928],"domain_scores_gemma":[0.999809,0.00001030773,0.00003577072,0.000005487952,0.00009189385,0.00004762255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005278371,0.0001944246,0.2113188,0.0008109669,0.00008913167,0.00181121,0.001028248,0.0005273061,0.7176878,0.0003038836,0.001685372,0.06401508],"study_design_scores_gemma":[0.00003301414,0.0003451638,0.9032329,0.0001605389,0.0001582884,0.0009591659,0.003762829,0.0005545454,0.07081319,0.00009427149,0.01983772,0.00004841734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848033,0.004242361,0.0006868399,0.0002405979,0.00003178812,0.000183279,0.004260471,0.00003885339,0.00551253],"genre_scores_gemma":[0.9799404,0.004810804,0.003525407,0.0002114316,0.00001860816,0.00004272151,0.005277382,0.00001429773,0.006159053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2415661,"threshold_uncertainty_score":0.4859775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01253344854493651,"score_gpt":0.1775816691279291,"score_spread":0.1650482205829926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}