{"id":"W2022911774","doi":"10.1002/gene.10021","title":"A cre recombinase transgene with mosaic, widespread tamoxifen‐inducible action","year":2002,"lang":"en","type":"article","venue":"genesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Cre recombinase; Transgene; Biology; Embryonic stem cell; Tamoxifen; Reporter gene; Molecular biology; Recombinase; Genetically modified mouse; Gene targeting; Gene; Cancer research; Gene expression; Genetics; Cancer; Recombination","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005467669,0.000781725,0.0007076359,0.0008498714,0.0003981669,0.0004781869,0.0009630921,0.0009442295,0.006149983],"category_scores_gemma":[0.0003088844,0.0004741055,0.0005187792,0.0006093563,0.000419946,0.0004533041,0.0006576298,0.0009599078,0.005485434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002226852,"about_ca_system_score_gemma":0.0004354359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003647625,"about_ca_topic_score_gemma":0.0007674354,"domain_scores_codex":[0.9996564,0.00003744637,0.00003601097,0.00007836505,0.0001485368,0.00004332916],"domain_scores_gemma":[0.9997771,0.00003152248,0.00006195868,0.00004311131,0.00003368031,0.00005251519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003431103,0.00002598969,0.00007742811,0.00005763914,0.000006357256,0.0001023751,0.00001272655,0.00003317165,0.9935285,0.000393992,0.0005473855,0.005179967],"study_design_scores_gemma":[0.0001345744,0.0006900429,0.003185,0.00003893256,0.000101443,0.005065192,0.00003086464,0.001253273,0.8740352,0.000428356,0.1150025,0.00003457698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3541154,0.008405725,0.5702295,0.0009968949,0.0006242635,0.003405267,0.009024263,0.01144005,0.04175857],"genre_scores_gemma":[0.5615382,0.01128548,0.3044695,0.0006229971,0.0001569728,0.002191286,0.01616143,0.001517741,0.1020563],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.006149983,"threshold_uncertainty_score":0.02057374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02273739907722964,"score_gpt":0.2762076102104862,"score_spread":0.2534702111332566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}