{"id":"W2022911774","doi":"10.1002/gene.10021","title":"A cre recombinase transgene with mosaic, widespread tamoxifen‐inducible action","year":2002,"lang":"en","type":"article","venue":"genesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Cre recombinase; Transgene; Biology; Embryonic stem cell; Tamoxifen; Reporter gene; Molecular biology; Recombinase; Genetically modified mouse; Gene targeting; Gene; Cancer research; Gene expression; Genetics; Cancer; Recombination","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006415606,0.0001684376,0.0001228758,0.00004466022,0.00007565205,0.00002020537,0.0001127107,0.0001198304,0.0002285967],"category_scores_gemma":[0.00001336597,0.000157643,0.00006936902,0.0001293725,0.00002604386,0.000004044323,0.00002069264,0.00005618492,0.00003472476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001175457,"about_ca_system_score_gemma":0.00001356789,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004142597,"about_ca_topic_score_gemma":0.00007744254,"domain_scores_codex":[0.9991368,0.00002184765,0.0001314308,0.0003480165,0.0001078527,0.0002540623],"domain_scores_gemma":[0.9994448,0.00000628913,0.00003094253,0.0003753386,0.00004157879,0.0001010809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004619758,0.00008367198,0.000863275,0.00003165536,0.00006535718,0.000008806885,0.0001013124,0.001478791,0.966028,0.000003929408,0.007108539,0.02418042],"study_design_scores_gemma":[0.0006287659,0.0003211046,0.001618712,0.00001371012,0.00004362877,0.00006184082,0.00007545522,0.0004036936,0.9500539,0.000006993883,0.04650071,0.0002714673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829616,0.002346419,0.01310854,0.000175918,0.0001785756,0.0001532999,0.00001495108,0.00003939566,0.001021303],"genre_scores_gemma":[0.9937366,0.0008521601,0.002022971,0.0001044781,0.0001805373,0.00004255275,0.00004828204,0.00003979263,0.002972602],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03939217,"threshold_uncertainty_score":0.6428494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02273739907722964,"score_gpt":0.2762076102104862,"score_spread":0.2534702111332566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}