{"id":"W2022914992","doi":"10.1021/ja8060326","title":"Kinetic Analysis of Arsenic−Metalation of Human Metallothionein: Significance of the Two-Domain Structure","year":2008,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Trace Elements in Health","field":"Nursing","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Arsenic; Metallothionein; Metalation; Stereochemistry; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002839743,0.0003107325,0.0002337577,0.0001601791,0.0000945256,0.0002020343,0.0002104048,0.0002092273,0.0007608874],"category_scores_gemma":[0.000417581,0.0001144635,0.0002611816,0.000250637,0.0001278047,0.0001642562,0.0001117239,0.0002697527,0.0002895029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003786139,"about_ca_system_score_gemma":0.0001438171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001224878,"about_ca_topic_score_gemma":0.0007693619,"domain_scores_codex":[0.9998124,0.00002535976,0.000009321892,0.00006425049,0.00006962409,0.00001913576],"domain_scores_gemma":[0.9997838,0.00007273282,0.00004660969,0.00002095384,0.00005254425,0.00002336862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004128006,0.00003244526,0.002901069,0.00008621931,0.0000505777,0.00004387918,0.00009397198,0.001456366,0.9904714,0.0001710379,0.00007712936,0.004203236],"study_design_scores_gemma":[0.00001007423,0.0002326673,0.01169561,0.000003292353,0.00002477835,0.0001977034,0.00003168048,0.01638651,0.9706383,0.00007282825,0.0006886541,0.00001789291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921101,0.0007970379,0.005940772,0.00003175806,0.000008297752,0.00002132077,0.0004102003,0.00008851847,0.0005920741],"genre_scores_gemma":[0.9956419,0.000378038,0.002730268,0.00001153973,0.000002981411,0.00001504626,0.0003786075,0.00001317537,0.0008284147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001224878,"threshold_uncertainty_score":0.002746999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0172737173989467,"score_gpt":0.30244448465436,"score_spread":0.2851707672554133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}