{"id":"W2022924415","doi":"10.1016/j.freeradbiomed.2004.12.006","title":"The biosynthesis of ascorbate protects isolated rat hepatocytes from cumene hydroperoxide-mediated oxidative stress","year":2004,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Vitamin C and Antioxidants Research","field":"Nursing","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University; Hôpital Saint-Luc; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cumene hydroperoxide; Glutathione; Biochemistry; Oxidative stress; Lipid peroxidation; Chemistry; Antioxidant; Ascorbic acid; Reactive oxygen species; Oxidative phosphorylation; Endogeny; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004568146,0.0002013275,0.000449761,0.00009040708,0.0002916556,0.000009413169,0.000363854,0.0002493833,0.0001134664],"category_scores_gemma":[0.002347744,0.0001061786,0.00004638901,0.0002214081,0.002390889,0.00005958499,0.0001053033,0.0003855609,0.00001768877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003433943,"about_ca_system_score_gemma":0.00004299254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001101344,"about_ca_topic_score_gemma":0.00009879383,"domain_scores_codex":[0.9982995,0.0003323755,0.0003931402,0.0003522349,0.0002033934,0.0004193177],"domain_scores_gemma":[0.9980196,0.001231151,0.0001374447,0.000350335,0.0000720083,0.0001894967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001050373,0.0001831778,0.006443004,0.00005791229,0.0002239303,0.00003604019,0.001071506,0.000001496256,0.965362,0.0008466426,0.0007188708,0.02400503],"study_design_scores_gemma":[0.006502002,0.003345774,0.01068319,0.001099535,0.0001145337,0.0000199545,0.0007596369,0.0004422445,0.955596,0.01670863,0.004419278,0.0003092002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796855,0.005491999,0.0003564108,0.01337821,0.0003545317,0.0004535242,0.00008879678,0.00005243596,0.0001386022],"genre_scores_gemma":[0.9977986,0.001424748,0.0001397448,0.0002676669,0.0002087155,0.00002317604,0.00006964982,0.00001574403,0.00005199838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02369582,"threshold_uncertainty_score":0.8809331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01478794023843675,"score_gpt":0.2890730474051227,"score_spread":0.2742851071666859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}