{"id":"W2022940890","doi":"10.1007/s00204-013-1180-8","title":"Mammalian toxicology and human exposures to the flame retardant 2,2′,6,6′-tetrabromo-4,4′-isopropylidenediphenol (TBBPA): implications for risk assessment","year":2013,"lang":"en","type":"review","venue":"Archives of Toxicology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":110,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Tetrabromobisphenol A; Toxicity; Brominated flame retardant; Reproductive toxicity; Population; Endocrine system; Developmental toxicity; Adverse effect; Physiology; Toxicology; Endocrine disruptor; Bioaccumulation; Reference dose; Pharmacology; Chemistry; Medicine; Risk assessment; Environmental chemistry; Fire retardant; Biology; Hormone; Environmental health; Internal medicine; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004556087,0.0008313076,0.001116828,0.001911259,0.0001745811,0.0005881503,0.000647638,0.0006800953,0.0018679],"category_scores_gemma":[0.0004411829,0.0002604264,0.0003849306,0.002537727,0.0002704381,0.0005820467,0.0004560596,0.0005899935,0.0008765394],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004281972,"about_ca_system_score_gemma":0.0008980583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003062942,"about_ca_topic_score_gemma":0.006065914,"domain_scores_codex":[0.9998426,0.00001690462,0.00002130896,0.00003202913,0.000075253,0.00001180047],"domain_scores_gemma":[0.9998109,0.00006102855,0.00004032872,0.000004925283,0.00006976443,0.00001318495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008445846,0.00007876291,0.0005764199,0.02021296,0.000165224,0.0001747977,0.00006255093,0.0004340407,0.006899728,0.001062692,0.01340367,0.9568446],"study_design_scores_gemma":[0.00002360971,0.0002022745,0.004759646,0.00363711,0.0004436221,0.001334041,0.0001665717,0.0001057459,0.00338836,0.001372385,0.9845324,0.00003430381],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002862174,0.9989279,0.00007474406,0.00007504482,0.00004713904,0.000002818509,0.00003314139,0.000003899136,0.0005489935],"genre_scores_gemma":[0.0009740948,0.9983278,0.0001012955,0.00005628439,0.00002779297,0.000003151464,0.00003293137,6.314094e-7,0.0004761074],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003062942,"threshold_uncertainty_score":0.006248713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03524462009825712,"score_gpt":0.3421406934180987,"score_spread":0.3068960733198415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}