{"id":"W2022940890","doi":"10.1007/s00204-013-1180-8","title":"Mammalian toxicology and human exposures to the flame retardant 2,2′,6,6′-tetrabromo-4,4′-isopropylidenediphenol (TBBPA): implications for risk assessment","year":2013,"lang":"en","type":"review","venue":"Archives of Toxicology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":110,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Tetrabromobisphenol A; Toxicity; Brominated flame retardant; Reproductive toxicity; Population; Endocrine system; Developmental toxicity; Adverse effect; Physiology; Toxicology; Endocrine disruptor; Bioaccumulation; Reference dose; Pharmacology; Chemistry; Medicine; Risk assessment; Environmental chemistry; Fire retardant; Biology; Hormone; Environmental health; Internal medicine; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005857832,0.0006367686,0.001682163,0.0002250038,0.000503584,0.00005304033,0.001565683,0.0003723999,0.0008778616],"category_scores_gemma":[0.0004234476,0.0004377333,0.0004258314,0.000271349,0.001070032,0.0001186564,0.001085463,0.0006114015,0.000126701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002193896,"about_ca_system_score_gemma":0.0001532982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001220014,"about_ca_topic_score_gemma":0.001335816,"domain_scores_codex":[0.9958739,0.0007950622,0.001165836,0.001026969,0.0002076339,0.0009305467],"domain_scores_gemma":[0.9958651,0.001481577,0.0009352965,0.001327508,0.000005717744,0.0003847943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000009472622,0.0001602078,0.000750046,0.0003470912,0.0002256199,0.000002506714,0.0003766302,0.000005244653,0.00349508,0.001046133,0.002156113,0.9914259],"study_design_scores_gemma":[0.0006108506,0.00272385,0.1375865,0.000402936,0.001171953,0.0002421269,0.00009942235,0.00001734329,0.0001865791,0.01048508,0.8456007,0.0008726376],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01565789,0.9259298,0.006804122,0.01030724,0.001597037,0.02324446,0.004844519,0.0002792104,0.01133568],"genre_scores_gemma":[0.07276863,0.8953378,0.02550054,0.0007085627,0.0004500863,0.002744087,0.00005412001,0.000263464,0.00217273],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9905532,"threshold_uncertainty_score":0.9998074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03524462009825712,"score_gpt":0.3421406934180987,"score_spread":0.3068960733198415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}