{"id":"W2022961047","doi":"10.1016/j.str.2004.01.008","title":"Crystal Structure of Mycoplasma arthritidis Mitogen Complexed with HLA-DR1 Reveals a Novel Superantigen Fold and a Dimerized Superantigen-MHC Complex","year":2004,"lang":"en","type":"article","venue":"Structure","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Superantigen; Major histocompatibility complex; T-cell receptor; Biology; Antigen; MHC restriction; Epitope; Cell biology; Chemistry; MHC class I; T cell; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001840973,0.0004664815,0.0006191304,0.0001639605,0.0006190251,0.0007534878,0.0008091118,0.0004867987,0.001905237],"category_scores_gemma":[0.0003577527,0.0002714068,0.0001546222,0.0003087696,0.0002666291,0.0003242664,0.000243161,0.00154008,0.0002548759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001013935,"about_ca_system_score_gemma":0.0007552771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003799571,"about_ca_topic_score_gemma":0.005573793,"domain_scores_codex":[0.9999005,0.00001432006,0.00000427818,0.00001684055,0.00003863778,0.00002547464],"domain_scores_gemma":[0.9998488,0.00004576885,0.00003954913,0.000005618725,0.00001618601,0.00004400906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00317058,0.001043894,0.01433052,0.001119566,0.0002555671,0.005154508,0.001059051,0.007618643,0.9242085,0.006485355,0.01655128,0.01900247],"study_design_scores_gemma":[0.002197471,0.001866907,0.1331351,0.0003038163,0.0005662238,0.01428253,0.00367139,0.1516304,0.6106433,0.00499543,0.07643468,0.0002728765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913202,0.002828076,0.001131292,0.0009600989,0.0001342036,0.00002611659,0.0008373996,0.0001703053,0.002592296],"genre_scores_gemma":[0.9895347,0.002119679,0.002358677,0.0003711474,0.00003764064,0.000033575,0.003029846,0.00003327263,0.002481617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003799571,"threshold_uncertainty_score":0.007554889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01078169201050924,"score_gpt":0.2143184080913646,"score_spread":0.2035367160808553,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}