{"id":"W2023006132","doi":"10.1002/gcc.21999","title":"Poly‐gene fusion transcripts and chromothripsis in prostate cancer","year":2012,"lang":"en","type":"article","venue":"Genes Chromosomes and Cancer","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency; Simon Fraser University; University of British Columbia","funders":"Canadian Institutes of Health Research; Pfizer","keywords":"Chromothripsis; Chromoplexy; Biology; Fusion gene; Genome; Gene; Genetics; Transcriptome; Computational biology; Cancer; Genome instability; Prostate cancer; DNA; Gene expression; DNA damage; PCA3","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008965353,0.0001917397,0.0001832208,0.0000400038,0.00008367895,0.0000272107,0.000074375,0.0001071614,0.00005407539],"category_scores_gemma":[0.000002292644,0.0001753712,0.00003956216,0.00007671164,0.00007604009,0.00001061114,0.0000834313,0.00006083666,9.155248e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002830655,"about_ca_system_score_gemma":0.00005700025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003790425,"about_ca_topic_score_gemma":0.0006511325,"domain_scores_codex":[0.9990367,0.00002311396,0.0001793316,0.0003019747,0.00008181501,0.0003770523],"domain_scores_gemma":[0.9996215,0.000003086074,0.00005628315,0.0001598772,0.00002449486,0.0001348111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003683851,0.00004426108,0.09823897,0.00007604241,0.00003798771,0.000001637777,0.0004830801,0.00001907932,0.806513,0.00002110085,0.0001040491,0.09442394],"study_design_scores_gemma":[0.002936007,0.0003030873,0.3495948,0.0001441274,0.0001036439,0.00009151232,0.0005644338,0.0005736041,0.5370046,0.00008610843,0.1075216,0.001076406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7978877,0.2013552,0.00001097068,0.0002246406,0.000225662,0.0001415279,0.00009582739,0.000005954018,0.00005252656],"genre_scores_gemma":[0.8926814,0.1061492,0.0001932154,0.0002366895,0.0002455641,0.00007210058,0.00004309854,0.00002783537,0.0003508803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2695084,"threshold_uncertainty_score":0.7151431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007591368027311139,"score_gpt":0.2372217416933058,"score_spread":0.2296303736659947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}