{"id":"W2023014460","doi":"10.1007/s00223-006-0102-7","title":"Differential Mechanisms of Transcriptional Regulation of the Mouse Osteocalcin Gene by Jun Family Members","year":2007,"lang":"en","type":"article","venue":"Calcified Tissue International","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Shriners Hospitals for Children - Canada","funders":"","keywords":"JUNB; Osteocalcin; Chromatin immunoprecipitation; Coactivator; Transcriptional regulation; Activator (genetics); Promoter; Molecular biology; Osteoblast; Chemistry; Transcription (linguistics); Regulation of gene expression; Transcription factor; c-jun; Cell biology; Gene expression; Biology; Gene; Biochemistry; Alkaline phosphatase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009740455,0.0001018647,0.0001118525,0.00004038408,0.00003036862,0.000006863418,0.0002453962,0.0001052971,0.0001857718],"category_scores_gemma":[0.00003561364,0.00008363195,0.0001146407,0.00005406035,0.0001019212,0.000005830413,0.00005138053,0.00004488519,0.000001746312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009810175,"about_ca_system_score_gemma":0.0000327447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003116403,"about_ca_topic_score_gemma":0.00001281767,"domain_scores_codex":[0.9990633,0.00002962924,0.0002938096,0.0001810289,0.0003190552,0.00011325],"domain_scores_gemma":[0.9994801,0.0000110675,0.0001311287,0.0001871626,0.0001413425,0.00004914645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001917073,0.00009696902,0.0001676977,0.000006973161,0.00005020839,2.717144e-7,0.00001818541,0.00004554569,0.9910726,0.00580701,0.001557238,0.0009855976],"study_design_scores_gemma":[0.0006054238,0.00003721754,0.02375741,0.000005361928,0.00002538629,0.000002565132,0.00003346959,0.00004098212,0.9683411,0.0005721322,0.006496846,0.00008216745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9137051,0.0002911845,0.08390172,0.00009720746,0.0005610931,0.0001214384,0.0003620771,0.000005562526,0.000954649],"genre_scores_gemma":[0.9965946,0.00001903485,0.0004755943,0.00009326343,0.0001497845,0.000005116695,0.0005185084,0.00001188985,0.002132202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08342612,"threshold_uncertainty_score":0.3410412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008920659354261092,"score_gpt":0.2463397670269575,"score_spread":0.2374191076726964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}