{"id":"W2023017320","doi":"10.1002/dvg.20282","title":"Cre‐conditional expression of constitutively active Notch1 in transgenic mice","year":2007,"lang":"en","type":"article","venue":"genesis","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Cre recombinase; Transgene; Biology; Genetically modified mouse; Notch signaling pathway; Cell biology; Embryonic stem cell; Molecular biology; Cre-Lox recombination; Neural tube; Embryo; Green fluorescent protein; Signal transduction; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001091231,0.001111151,0.0007509259,0.001586665,0.0004926771,0.0007575657,0.001749782,0.001688433,0.006188777],"category_scores_gemma":[0.0003642743,0.001312723,0.0007546764,0.000670441,0.0008555089,0.0007028831,0.0007429668,0.002705667,0.003718513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006503239,"about_ca_system_score_gemma":0.0005555819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006491502,"about_ca_topic_score_gemma":0.001150514,"domain_scores_codex":[0.9991704,0.0001037654,0.0001101985,0.0002627479,0.0002166884,0.0001362366],"domain_scores_gemma":[0.9994233,0.00009915509,0.0001943029,0.00009019319,0.00004860252,0.0001445372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001201645,0.00009054463,0.0001097784,0.00009848212,0.00001571939,0.0001930784,0.00005338528,0.0001247971,0.9942128,0.001052952,0.0005353142,0.003392961],"study_design_scores_gemma":[0.0003077024,0.000447607,0.001779661,0.00008901053,0.0001108566,0.00284653,0.000045448,0.002169321,0.9522573,0.000482255,0.03942475,0.0000395333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6952043,0.007275468,0.235474,0.001915441,0.001179149,0.0031443,0.01899485,0.01382902,0.02298341],"genre_scores_gemma":[0.7141536,0.009974524,0.1667053,0.001172384,0.000300336,0.00451243,0.02147376,0.002485455,0.07922219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006188777,"threshold_uncertainty_score":0.02070355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007572522883307811,"score_gpt":0.2484434802457533,"score_spread":0.2408709573624455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}