{"id":"W2023066607","doi":"10.1016/j.vetmic.2011.08.015","title":"In vitro killing of Escherichia coli, Staphylococcus pseudintermedius and Pseudomonas aeruginosa by enrofloxacin in combination with its active metabolite ciprofloxacin using clinically relevant drug concentrations in the dog and cat","year":2011,"lang":"en","type":"article","venue":"Veterinary Microbiology","topic":"Antibiotics Pharmacokinetics and Efficacy","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Royal University Hospital","funders":"American College of Veterinary Internal Medicine","keywords":"Enrofloxacin; Staphylococcus pseudintermedius; Ciprofloxacin; Microbiology; Biology; Staphylococcus intermedius; Pseudomonas aeruginosa; Antimicrobial; Antibacterial agent; Staphylococcus; Antibiotics; Pharmacology; Staphylococcus aureus; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008927712,0.0004136511,0.0006539729,0.0003357164,0.0002084398,0.0004511682,0.0004239846,0.0005096974,0.0009224389],"category_scores_gemma":[0.001174396,0.0005069727,0.0004037628,0.0002496901,0.000563534,0.000508148,0.0002211303,0.0005039464,0.0002459321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005857403,"about_ca_system_score_gemma":0.0005195972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002954606,"about_ca_topic_score_gemma":0.004304864,"domain_scores_codex":[0.9990553,0.0004597872,0.00008434289,0.0001091917,0.0001605292,0.0001308894],"domain_scores_gemma":[0.9991768,0.000419456,0.0001243797,0.00008296209,0.00008622457,0.0001101807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01418709,0.001526538,0.004822474,0.0002187131,0.00006463291,0.0003282507,0.0004891234,0.001239898,0.9672093,0.0001785769,0.0001852433,0.009550068],"study_design_scores_gemma":[0.0003485262,0.0780896,0.02519698,0.00002739799,0.000163369,0.0008572096,0.0003826767,0.004551557,0.8888915,0.00007643738,0.00137636,0.0000384874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991534,0.0003997747,0.000158991,0.00002955294,0.00001038582,0.00001162246,0.0000435049,0.000003921745,0.0001889361],"genre_scores_gemma":[0.9980463,0.0005163554,0.0005295919,0.00001784466,0.0000115432,0.00001403536,0.000127457,0.000004724804,0.0007320534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002954606,"threshold_uncertainty_score":0.005874813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03150488086835599,"score_gpt":0.3026706334478118,"score_spread":0.2711657525794557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}