{"id":"W2023066607","doi":"10.1016/j.vetmic.2011.08.015","title":"In vitro killing of Escherichia coli, Staphylococcus pseudintermedius and Pseudomonas aeruginosa by enrofloxacin in combination with its active metabolite ciprofloxacin using clinically relevant drug concentrations in the dog and cat","year":2011,"lang":"en","type":"article","venue":"Veterinary Microbiology","topic":"Antibiotics Pharmacokinetics and Efficacy","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Royal University Hospital","funders":"American College of Veterinary Internal Medicine","keywords":"Enrofloxacin; Staphylococcus pseudintermedius; Ciprofloxacin; Microbiology; Biology; Staphylococcus intermedius; Pseudomonas aeruginosa; Antimicrobial; Antibacterial agent; Staphylococcus; Antibiotics; Pharmacology; Staphylococcus aureus; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004405694,0.000190164,0.0004623018,0.0001793958,0.00003505732,0.0000073714,0.0000961063,0.0001130708,0.000008279368],"category_scores_gemma":[0.00004111679,0.0001413065,0.00002912618,0.0002483523,0.0003264921,0.00008226111,0.00007136178,0.0003095935,6.116228e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004119592,"about_ca_system_score_gemma":0.00007142917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002020473,"about_ca_topic_score_gemma":0.0000180775,"domain_scores_codex":[0.9984898,0.0002959117,0.00053561,0.0003367345,0.00005167017,0.0002902618],"domain_scores_gemma":[0.9993489,0.0001944745,0.0001896042,0.0001458993,0.00006517168,0.00005589998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001846469,0.0004559985,0.008538248,0.00007211924,0.00003369716,0.00011477,0.004639846,0.000003003001,0.9839225,0.00006747189,0.00001429998,0.0002915195],"study_design_scores_gemma":[0.0132358,0.002936974,0.08255553,0.0004002432,0.000172505,0.0003726284,0.003056305,0.004179229,0.8919811,0.00007959417,0.0005485506,0.0004814975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980114,0.0007030261,0.00008308185,0.0002758896,0.00008570066,0.0007268898,0.00006468253,0.000006092858,0.00004325364],"genre_scores_gemma":[0.9969902,0.0008345578,0.00176543,0.0003085673,0.00001652534,0.000009677881,0.00004912752,0.00001537186,0.00001052056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09194142,"threshold_uncertainty_score":0.5762313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03150488086835599,"score_gpt":0.3026706334478118,"score_spread":0.2711657525794557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}