{"id":"W2023072606","doi":"10.1016/j.clgc.2014.06.001","title":"A Phase II Study of GW786034 (Pazopanib) With or Without Bicalutamide in Patients With Castration-Resistant Prostate Cancer","year":2014,"lang":"en","type":"article","venue":"Clinical Genitourinary Cancer","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; Queen's University","funders":"National Cancer Institute","keywords":"Bicalutamide; Medicine; Pazopanib; Prostate cancer; Castration; Oncology; Internal medicine; Cancer; Urology; Androgen receptor; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001128837,0.001862266,0.003929333,0.0006691397,0.0004925278,0.001123162,0.001272098,0.001429345,0.005170114],"category_scores_gemma":[0.0009594333,0.0009628201,0.002029739,0.0007921748,0.001496194,0.001481205,0.00049736,0.004680798,0.001341269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009334672,"about_ca_system_score_gemma":0.001996328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001902878,"about_ca_topic_score_gemma":0.005029755,"domain_scores_codex":[0.9994388,0.0002510933,0.00002648504,0.0001100635,0.00003814096,0.0001353817],"domain_scores_gemma":[0.9993591,0.00009546031,0.00008326363,0.00006058991,0.0000271589,0.0003744671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8836404,0.03150146,0.00172841,0.0006357536,0.001247762,0.0001465513,0.0001344333,0.001479955,0.02129413,0.0002164583,0.002682,0.05529278],"study_design_scores_gemma":[0.7866248,0.2050688,0.004330739,0.00001791574,0.0005266226,0.0001335135,0.00004142257,0.000593416,0.001186443,0.000147281,0.001297526,0.0000314066],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900184,0.002832144,0.0005493803,0.00070001,0.0003678908,0.001802559,0.001207512,0.0001672411,0.002354976],"genre_scores_gemma":[0.9875318,0.003058427,0.001499935,0.0009952561,0.0003677378,0.001844299,0.002152682,0.00006458885,0.002485197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005170114,"threshold_uncertainty_score":0.01729572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06198738149956967,"score_gpt":0.4255199717726553,"score_spread":0.3635325902730856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}