{"id":"W2023095276","doi":"10.1016/s0006-3495(03)74682-7","title":"Computational Study on the Function of Water within a β-Helix Antifreeze Protein Dimer and in the Process of Ice-Protein Binding","year":2003,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Antifreeze protein; Molecule; Dimer; Chemistry; Water ice; Binding energy; Water dimer; Chemical physics; Properties of water; Antifreeze; Crystallography; Biophysics; Astrobiology; Hydrogen bond; Biology; Physics; Biochemistry; Organic chemistry; Atomic physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003225284,0.00007474906,0.00009977443,0.00001507526,0.0001051915,0.00001543176,0.000129235,0.00002374755,0.00007316789],"category_scores_gemma":[0.00005424101,0.00002877157,0.0000353248,0.000172475,0.0001982464,0.00006293276,0.00002791217,0.0001999126,0.00001268453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001104998,"about_ca_system_score_gemma":0.00000532819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009642283,"about_ca_topic_score_gemma":0.000001436182,"domain_scores_codex":[0.9990764,0.0001727973,0.0002059818,0.0001158899,0.0003226183,0.0001063465],"domain_scores_gemma":[0.9997337,0.00007193215,0.00009016669,0.00006217695,0.00001404231,0.00002790758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006266842,0.0006346157,0.001092319,0.000003521968,0.000007957478,0.000001071558,0.0005092384,0.0007857694,0.9963948,0.0004167289,0.000005326979,0.00008595779],"study_design_scores_gemma":[0.0006839122,0.001241834,0.1626483,0.00006335379,0.00002212567,0.000005780156,0.002197331,0.001040332,0.808412,0.02352142,0.00001363222,0.0001499035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992022,0.000001398947,0.00007453972,0.0002934648,0.000009981462,0.0003011631,0.000002080726,0.000002085956,0.000113094],"genre_scores_gemma":[0.9998195,1.674283e-7,0.00007516847,0.00005388693,0.0000171957,0.000017129,8.571978e-7,0.000002487662,0.00001363086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1879828,"threshold_uncertainty_score":0.117327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02132909585682234,"score_gpt":0.2368293364772051,"score_spread":0.2155002406203827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}