{"id":"W2023098027","doi":"10.1042/cs20030139","title":"Activation of the right ventricular endothelin (ET) system in the monocrotaline model of pulmonary hypertension: response to chronic ETA receptor blockade","year":2003,"lang":"en","type":"article","venue":"Clinical Science","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute","funders":"Heart and Stroke Foundation of Canada","keywords":"Right ventricular hypertrophy; Pulmonary hypertension; Internal medicine; Medicine; Ventricle; Endothelin receptor; Endocrinology; Blockade; Receptor; Muscle hypertrophy; Endothelin 1; Endothelin receptor antagonist; Saline; Receptor antagonist; Antagonist","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000409048,0.0007509961,0.001184328,0.0004272085,0.0002535102,0.0004577403,0.000494446,0.0005865557,0.001721388],"category_scores_gemma":[0.0002579885,0.0003285733,0.0003776021,0.0002410036,0.0008691173,0.0008038117,0.0004444897,0.001460469,0.0003701704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004563605,"about_ca_system_score_gemma":0.0004430415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005484633,"about_ca_topic_score_gemma":0.001150515,"domain_scores_codex":[0.99951,0.00006611165,0.00004979393,0.0001001181,0.0001324649,0.0001413692],"domain_scores_gemma":[0.9993506,0.00006380514,0.0001935197,0.00007616488,0.00003760438,0.0002783258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004076004,0.000486367,0.0004425285,0.00008883113,0.00002341408,0.0002486327,0.00005395589,0.00007266591,0.9924093,0.00007569474,0.00004357895,0.001978886],"study_design_scores_gemma":[0.0005816563,0.02634056,0.01779818,0.00002230025,0.0001314301,0.001053941,0.0002249633,0.001764402,0.9503751,0.0001125203,0.001565483,0.00002940196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962268,0.001306247,0.001467076,0.0001307345,0.00008730434,0.00006577175,0.0001734893,0.00004904911,0.0004935462],"genre_scores_gemma":[0.9942322,0.001190577,0.001897103,0.00009356884,0.00009765744,0.0001592492,0.0003079252,0.00001926455,0.002002454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001721388,"threshold_uncertainty_score":0.005758584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06212945401882761,"score_gpt":0.3554937806813167,"score_spread":0.293364326662489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}