{"id":"W2023105352","doi":"10.1097/01.hjh.0000379699.52889.7c","title":"BLOCKADE OF TACHYKININ NK-3 RECEPTOR REVERSES HYPERTENSION THROUGH A DOPAMINERGIC MECHANISM IN THE VENTRAL TEGMENTAL AREA OF SPONTANEOUSLY HYPERTENSIVE RATS: PP.29.161","year":2010,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Ventral tegmental area; Internal medicine; Endocrinology; Medicine; Raclopride; Agonist; Dopamine; Dopaminergic; Mean arterial pressure; Receptor; Heart rate; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001442911,0.0004622025,0.0004818816,0.0002585077,0.0001497751,0.0002454437,0.0003345107,0.0003381511,0.001934115],"category_scores_gemma":[0.0001540048,0.0002458997,0.0003719298,0.0001205996,0.0003846168,0.0004233378,0.0001975738,0.001340941,0.00063875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002260993,"about_ca_system_score_gemma":0.0002982017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008506426,"about_ca_topic_score_gemma":0.00165182,"domain_scores_codex":[0.9998802,0.00001772193,0.00001654485,0.00001821017,0.00002466272,0.00004259971],"domain_scores_gemma":[0.9998258,0.00001404048,0.00004943315,0.00001838613,0.0000139571,0.00007837975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001305471,0.0003096601,0.0002191555,0.00005626801,0.00001592821,0.0001423489,0.00003271662,0.0000466303,0.9948454,0.0001101805,0.0001141227,0.002802128],"study_design_scores_gemma":[0.0004552727,0.00794007,0.01569185,0.0000244927,0.00008270693,0.0006237438,0.0001480034,0.001652975,0.970238,0.0001631362,0.002956466,0.00002323728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969408,0.0008414603,0.0007424137,0.0001770202,0.00007303851,0.00003165953,0.0002601979,0.00008787697,0.0008454428],"genre_scores_gemma":[0.9905381,0.00196262,0.001673041,0.000146305,0.00006137681,0.0001174059,0.0007069775,0.00003780324,0.004756298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001934115,"threshold_uncertainty_score":0.006470263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01876763216835524,"score_gpt":0.2237025806556424,"score_spread":0.2049349484872872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}