{"id":"W2023156689","doi":"10.1097/00007890-201007272-00006","title":"BK VIRUS HIGH LEVEL REPLICATION IN VITRO REDUCED BY CYCLOSPORINE A, PROXIMAL TUBULE CELL TYPE AND CULTURE ENVIRONMENT (POLARITY) BUT NOT BY TACROLIMUS","year":2010,"lang":"en","type":"article","venue":"Transplantation","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre","funders":"","keywords":"In vitro; Tacrolimus; Polarity (international relations); Cell culture; Virology; Replication (statistics); Chemistry; Cell biology; Cell; Biology; Molecular biology; Medicine; Transplantation; Internal medicine; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003777457,0.0003610364,0.0004642133,0.0004577455,0.0004719486,0.0008877478,0.0003654391,0.0002609999,0.003711396],"category_scores_gemma":[0.000426831,0.000350977,0.0004249456,0.0002882566,0.0003877923,0.0004323188,0.0004238571,0.001016235,0.001084171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008908882,"about_ca_system_score_gemma":0.001085808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01436293,"about_ca_topic_score_gemma":0.02503921,"domain_scores_codex":[0.9993836,0.0001228541,0.00005623199,0.00007660185,0.0001618353,0.0001989241],"domain_scores_gemma":[0.9992193,0.0002945007,0.00006579653,0.0001278249,0.0001357854,0.0001567803],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004337847,0.00008131792,0.0002772716,0.00002466614,0.000004984933,0.00003157288,0.00004585038,0.00004717096,0.9979886,0.0001124214,0.0001309866,0.0008214159],"study_design_scores_gemma":[0.00005849656,0.0005531808,0.009572667,0.000009934163,0.00001850859,0.0001432067,0.00009747218,0.00107523,0.986415,0.00006122009,0.001985462,0.000009739111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894962,0.001688245,0.002019037,0.0001931859,0.0001104637,0.0000542616,0.0007222953,0.000101586,0.005614852],"genre_scores_gemma":[0.9881912,0.0006803105,0.00214008,0.00007488737,0.00003875765,0.00004344801,0.001801493,0.0000483535,0.006981503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01436293,"threshold_uncertainty_score":0.02855867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009785769830601487,"score_gpt":0.2290952678228006,"score_spread":0.2193094979921991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}