{"id":"W2023215532","doi":"10.4161/auto.5407","title":"HspB8 and Bag3: A new chaperone complex targeting misfolded proteins to macroautophagy","year":2008,"lang":"en","type":"review","venue":"Autophagy","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":233,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"BAG3; Co-chaperone; WW domain; Biology; Chaperone (clinical); Cell biology; Autophagy; Protein folding; Heat shock protein; Hsp70; Biochemistry; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000388707,0.001012788,0.001055315,0.001675501,0.0002232019,0.0007514464,0.000915975,0.00112952,0.002616194],"category_scores_gemma":[0.0003203001,0.0002376779,0.0002303863,0.001862052,0.00049343,0.001630608,0.000603823,0.001321261,0.003446622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007318782,"about_ca_system_score_gemma":0.0006754594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005557895,"about_ca_topic_score_gemma":0.0008591826,"domain_scores_codex":[0.9998944,0.00001156224,0.00001391364,0.00002561615,0.00004398659,0.00001047154],"domain_scores_gemma":[0.9998462,0.00003230494,0.00002674919,0.000008035639,0.00005437271,0.00003234227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001163638,0.0000736946,0.0002515808,0.006021045,0.0000712469,0.0004005903,0.00004385733,0.0004055962,0.008192202,0.004669058,0.03876889,0.9409859],"study_design_scores_gemma":[0.00002351055,0.00007247391,0.001002089,0.0005335984,0.00003849758,0.002057502,0.00003052536,0.00008726046,0.001400696,0.001926459,0.9928132,0.00001424713],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003247705,0.9971743,0.0004706036,0.0003457521,0.0003147798,0.000004956245,0.00001579901,0.00002098059,0.001328051],"genre_scores_gemma":[0.001460678,0.9950537,0.0004965123,0.0002813606,0.0002504381,0.00001061173,0.00005656412,0.000003624067,0.002386547],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002616194,"threshold_uncertainty_score":0.008752048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05884697163149313,"score_gpt":0.3544047724719513,"score_spread":0.2955578008404581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}