{"id":"W2023276278","doi":"10.1007/s12032-015-0490-5","title":"ERK1/2 promoted proliferation and inhibited apoptosis of human cervical cancer cells and regulated the expression of c-Fos and c-Jun proteins","year":2015,"lang":"en","type":"article","venue":"Medical Oncology","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"HeLa; Apoptosis; Cell cycle; Cell growth; MAPK/ERK pathway; Flow cytometry; Cancer research; Cell; Kinase; Western blot; Biology; Cancer; Cancer cell; Molecular biology; Chemistry; Cell biology; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009061201,0.0004050867,0.0001805358,0.000408369,0.0002434203,0.0001565589,0.0001266959,0.0001449602,0.002544813],"category_scores_gemma":[0.00006426952,0.0001081009,0.0002622466,0.0001955954,0.0001332504,0.0001345194,0.0001275767,0.0005265566,0.000433263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002192333,"about_ca_system_score_gemma":0.0003164324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008087264,"about_ca_topic_score_gemma":0.001652013,"domain_scores_codex":[0.9999356,0.000008642532,0.000003418867,0.00000754381,0.00001571622,0.00002901393],"domain_scores_gemma":[0.9999746,0.000003347456,0.000004015097,0.000003399107,0.000007452097,0.000007132969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003543565,0.000160566,0.0004000878,0.0001347418,0.00001090201,0.0001201193,0.00003186025,0.0001034681,0.9923119,0.0003066994,0.0002533969,0.005811788],"study_design_scores_gemma":[0.00006858732,0.0004794847,0.008671366,0.00001173441,0.00003767867,0.0006078171,0.00006707937,0.0009272287,0.9809617,0.000202279,0.007957733,0.0000072122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866214,0.003717043,0.001840517,0.0002540905,0.00008151017,0.00005753077,0.0005545507,0.00008736212,0.006785991],"genre_scores_gemma":[0.988642,0.002420129,0.0007390316,0.00007178653,0.00002280382,0.00004022111,0.0005369601,0.000009874597,0.007517136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002544813,"threshold_uncertainty_score":0.008513272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01948764784642646,"score_gpt":0.285930108448547,"score_spread":0.2664424606021205,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}