{"id":"W2023347597","doi":"10.1016/j.micinf.2010.07.001","title":"Innate inflammatory response to the malarial pigment hemozoin","year":2010,"lang":"en","type":"review","venue":"Microbes and Infection","topic":"Malaria Research and Control","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Hemozoin; Biology; Heme; Innate immune system; Malaria; Plasmodium (life cycle); Detoxification (alternative medicine); Metabolite; Pigment; Damp; Inflammatory response; Plasmodium falciparum; Microbiology; Immunology; Inflammation; Biochemistry; Parasite hosting; Immune system; Chemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004647162,0.001101212,0.001354268,0.00127405,0.0002416022,0.000788864,0.0005775559,0.0007842029,0.002527281],"category_scores_gemma":[0.0004133752,0.0002621833,0.0002967768,0.001345079,0.0006248772,0.0009885248,0.0006397113,0.00176522,0.002060097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005772143,"about_ca_system_score_gemma":0.000872331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008647434,"about_ca_topic_score_gemma":0.002013606,"domain_scores_codex":[0.9998795,0.00001898885,0.00001724394,0.00002140584,0.00004884925,0.00001393006],"domain_scores_gemma":[0.9997638,0.00008601791,0.00004593194,0.000007360066,0.00006369191,0.00003328132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001566561,0.00007044633,0.0001848443,0.008839645,0.00005803224,0.0001656794,0.00003740934,0.0002460475,0.008350512,0.002396681,0.03328889,0.9462052],"study_design_scores_gemma":[0.0000353508,0.0001157756,0.001241532,0.001487894,0.00008410243,0.001004821,0.00005204667,0.00008899191,0.001872845,0.001553383,0.9924445,0.00001883281],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001287284,0.9983581,0.0001739229,0.0002139222,0.0002826581,0.00000467332,0.00001655751,0.000006420174,0.0008151612],"genre_scores_gemma":[0.0007651928,0.997506,0.0002293564,0.0001883471,0.0002807969,0.000007407381,0.00003329237,0.000001232755,0.0009885489],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002527281,"threshold_uncertainty_score":0.008454561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01684540491511284,"score_gpt":0.3078695137132675,"score_spread":0.2910241087981547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}