{"id":"W2023460039","doi":"10.1007/s00134-011-2234-0","title":"WNT/β-catenin signaling is modulated by mechanical ventilation in an experimental model of acute lung injury","year":2011,"lang":"en","type":"article","venue":"Intensive Care Medicine","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Instituto de Salud Carlos III; Canadian Institutes of Health Research; Fundación Canaria de Investigación y Salud","keywords":"Medicine; Sepsis; Lung; Mechanical ventilation; Wnt signaling pathway; Tidal volume; Pathology; Inflammation; Perforation; Internal medicine; Signal transduction; Respiratory system; Biology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004877369,0.0006272132,0.0006191824,0.0007159478,0.0005540525,0.0006078198,0.0005674214,0.0008650223,0.002178421],"category_scores_gemma":[0.0003537899,0.000345908,0.0007456725,0.0004525682,0.001367917,0.0007123731,0.0003606366,0.002402004,0.000262562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008458537,"about_ca_system_score_gemma":0.0005090888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006004248,"about_ca_topic_score_gemma":0.001063347,"domain_scores_codex":[0.9994249,0.0001276191,0.00005646389,0.00008706105,0.0001073601,0.0001966221],"domain_scores_gemma":[0.9995951,0.00005992935,0.0001429735,0.00005085886,0.00002129944,0.0001298559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007121648,0.0009786091,0.0005426295,0.00008650698,0.00002384766,0.0002842469,0.00008041826,0.0001468186,0.9885215,0.0004513287,0.0001086341,0.001653974],"study_design_scores_gemma":[0.0004648997,0.006796614,0.01009624,0.00002718866,0.00009908325,0.0004019598,0.0002469452,0.002071261,0.9782493,0.0002930389,0.001230594,0.00002268829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974618,0.0008075407,0.0008598964,0.0001995084,0.00007918462,0.00004559458,0.0001571412,0.0000261254,0.0003633027],"genre_scores_gemma":[0.9965973,0.0005811124,0.0008472853,0.0000739603,0.00003434105,0.0001758935,0.000270338,0.000009879871,0.001409895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002178421,"threshold_uncertainty_score":0.007287562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02478037278622088,"score_gpt":0.2957989432579421,"score_spread":0.2710185704717213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}