{"id":"W2023475282","doi":"10.1212/wnl.0b013e3181e0f7e6","title":"Cardiotoxicity and other adverse events associated with mitoxantrone treatment for MS","year":2010,"lang":"en","type":"article","venue":"Neurology","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Mitoxantrone; Cardiotoxicity; Medicine; Cumulative dose; Ejection fraction; Cumulative incidence; Adverse effect; Internal medicine; Odds ratio; Anemia; Confidence interval; Surgery; Toxicity; Chemotherapy; Heart failure; Cohort","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001083094,0.0001722965,0.0004460179,0.0008251797,0.0002742813,0.0003265207,0.0001768869,0.0002670845,0.001010303],"category_scores_gemma":[0.003830578,0.00009010691,0.0004674771,0.0009733977,0.0002692585,0.0001577861,0.0001824922,0.0002929863,0.0001273256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004115265,"about_ca_system_score_gemma":0.0003641509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001154295,"about_ca_topic_score_gemma":0.002510595,"domain_scores_codex":[0.9990851,0.0003553513,0.0001573444,0.000102681,0.0002337779,0.00006577389],"domain_scores_gemma":[0.9937932,0.001848637,0.003622635,0.0001199514,0.0003760958,0.0002393133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002692985,0.00001715468,0.9861478,0.000101024,0.0001088863,0.0006338908,0.00002862784,0.00009450346,0.0005898251,0.00001008546,0.0001336512,0.01186528],"study_design_scores_gemma":[0.00002056414,0.0003471137,0.9908693,0.00004659646,0.0001388328,0.007273297,0.00002786807,0.0001793975,0.0005148242,0.00001779053,0.0005598021,0.000004683711],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853421,0.01230318,0.0004638339,0.0001535238,0.000007863375,0.0000584101,0.000489037,0.00002822104,0.001153785],"genre_scores_gemma":[0.9969761,0.002155632,0.0003020324,0.00006765591,0.00002995689,0.00001993054,0.0003427558,0.000003041659,0.0001029766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001154295,"threshold_uncertainty_score":0.005728006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03902268756408058,"score_gpt":0.3153190142170568,"score_spread":0.2762963266529763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}