{"id":"W2023542419","doi":"10.1016/j.bbi.2009.11.007","title":"Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion","year":2009,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Spinal Cord Injury Research","field":"Medicine","cited_by":224,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Université Laval","keywords":"CXCL1; CXCL2; Neuroinflammation; Chemokine; Proinflammatory cytokine; Inflammation; Immunology; CCL2; Monocyte; Spinal cord injury; Microglia; Infiltration (HVAC); Chemokine receptor; Biology; Cell biology; Spinal cord; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001878414,0.0001865434,0.0002707622,0.0002041569,0.0001500529,0.00007296803,0.0002366869,0.000119736,0.00001191662],"category_scores_gemma":[0.0003274108,0.0001287579,0.00003596859,0.0002632788,0.0001851432,0.0003530061,0.00008781807,0.0008219624,0.000001144537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006947317,"about_ca_system_score_gemma":0.00006454904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001973529,"about_ca_topic_score_gemma":0.0001000763,"domain_scores_codex":[0.9977995,0.0008260165,0.0005075398,0.00021656,0.000359125,0.0002912157],"domain_scores_gemma":[0.9991251,0.0001417493,0.0001621918,0.000387855,0.00009882538,0.00008424345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002695363,0.0003332141,0.1789705,0.00005854914,0.000005208617,0.00001303323,0.001622225,3.066588e-7,0.718662,0.00005002122,0.00002096815,0.09756861],"study_design_scores_gemma":[0.001397496,0.005871361,0.9189804,0.000134365,0.00002667879,0.00003306855,0.002878661,0.00003679415,0.07046129,0.00002932043,0.00003309554,0.0001175148],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977309,0.0002487464,0.000003027723,0.0007566417,0.00001904898,0.001166585,0.0000152039,0.00002076077,0.00003910113],"genre_scores_gemma":[0.9994405,0.0001787348,0.0000542453,0.0001258783,0.00004021394,0.00007372815,0.00005496511,0.00001349615,0.0000182198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7400098,"threshold_uncertainty_score":0.5250594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03903689887094849,"score_gpt":0.3507822187808692,"score_spread":0.3117453199099207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}