{"id":"W2023606464","doi":"10.1007/s00262-005-0043-4","title":"Morphological appearance, content of extracellular matrix and vascular density of lung metastases predicts permissiveness to infiltration by adoptively transferred natural killer and T cells","year":2005,"lang":"en","type":"article","venue":"Cancer Immunology Immunotherapy","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Cancer Institute; Stiftelsen Jubileumsklinikens Forskningsfond mot Cancer; Cancer Research Society","keywords":"Infiltration (HVAC); Lewis lung carcinoma; Extracellular matrix; Pathology; Lung; Laminin; Fibronectin; Carcinoma; Adoptive cell transfer; Biology; CD8; Cancer research; Chemistry; Medicine; Immune system; Metastasis; T cell; Cancer; Immunology; Cell biology; Internal medicine; Materials science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002509463,0.0002977172,0.0006410515,0.0001676648,0.0001447643,0.00001251163,0.0001703191,0.0003169259,0.0004758639],"category_scores_gemma":[0.00002604159,0.0002617182,0.0001410921,0.0001459623,0.0005496509,0.0002255449,0.0000406859,0.0003603822,0.00001002294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006677501,"about_ca_system_score_gemma":0.00005125043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002990373,"about_ca_topic_score_gemma":0.000007521813,"domain_scores_codex":[0.9982843,0.00032067,0.0006155418,0.0003981005,0.00006518264,0.0003162118],"domain_scores_gemma":[0.9991457,0.0000738444,0.0002518683,0.0002732761,0.0002289505,0.00002628835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002273705,0.0001903572,0.001399815,0.00004000444,0.0009017529,0.000001127393,0.0009163807,0.0000433115,0.9810582,0.0001251241,0.0007217284,0.01232854],"study_design_scores_gemma":[0.004453399,0.0006084307,0.04670231,0.0001210934,0.0001082562,0.00007291533,0.0004595921,0.00004331613,0.908434,0.000003927208,0.03869821,0.0002945317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7685474,0.227659,0.001856116,0.0002055059,0.00119954,0.0004610257,0.00003025961,0.00003141495,0.000009825372],"genre_scores_gemma":[0.982866,0.0142438,0.0001536154,0.0001444595,0.00001553225,0.0000651919,0.00007167768,0.00002405605,0.002415689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2143186,"threshold_uncertainty_score":0.9999835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01374117931035333,"score_gpt":0.2512170495308257,"score_spread":0.2374758702204723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}