{"id":"W2023659884","doi":"10.1084/jem.20052056","title":"Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens","year":2006,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":305,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Biology; Antigen; Immune system; Leishmania; FOXP3; Immunology; Leishmania major; Natural killer T cell; T cell; Cell biology; Virology; Parasite hosting","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001822557,0.0002055814,0.0001968951,0.0001895592,0.0001087215,0.0001994346,0.0001333722,0.0001647144,0.002419342],"category_scores_gemma":[0.0002362284,0.0001274045,0.0001364893,0.00006901013,0.00029821,0.0001911307,0.0001309652,0.000482155,0.0004413383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009720138,"about_ca_system_score_gemma":0.0001542298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001093178,"about_ca_topic_score_gemma":0.0002177715,"domain_scores_codex":[0.9998832,0.00001867927,0.000009410797,0.00002780502,0.00002542159,0.00003549471],"domain_scores_gemma":[0.9998472,0.00003289551,0.00004047984,0.00002435019,0.00001752825,0.00003750521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000340299,0.00006755827,0.001940919,0.00007505913,0.000004792497,0.000300195,0.00004030028,0.00008972442,0.9885872,0.000163668,0.00008480278,0.008305479],"study_design_scores_gemma":[0.0003544447,0.002192305,0.07403434,0.00005024995,0.00008748041,0.00851777,0.0002045707,0.003999483,0.9000061,0.001394297,0.009135045,0.00002395263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943817,0.001119632,0.002214808,0.00005006143,0.00002932498,0.0000308755,0.0001128943,0.0001470175,0.001913699],"genre_scores_gemma":[0.9967982,0.0003962367,0.001241065,0.00005639825,0.00002638759,0.00002325643,0.0001758831,0.00001644786,0.001266253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002419342,"threshold_uncertainty_score":0.008093536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01065519061887264,"score_gpt":0.2348314463343701,"score_spread":0.2241762557154975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}