{"id":"W2023659884","doi":"10.1084/jem.20052056","title":"Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens","year":2006,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":305,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Biology; Antigen; Immune system; Leishmania; FOXP3; Immunology; Leishmania major; Natural killer T cell; T cell; Cell biology; Virology; Parasite hosting","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003032848,0.0002615941,0.0005394586,0.0001968807,0.0002756623,0.000007734854,0.0003701514,0.0002033371,0.0004698711],"category_scores_gemma":[0.00003148794,0.0001561484,0.000165928,0.0001809571,0.0007276671,0.00008182242,0.00006767418,0.0004990499,0.00006808513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009488662,"about_ca_system_score_gemma":0.00004292125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009897771,"about_ca_topic_score_gemma":0.00001095868,"domain_scores_codex":[0.9983785,0.0002448647,0.000726765,0.0001635997,0.00008031283,0.0004059306],"domain_scores_gemma":[0.9985051,0.0003171282,0.0006970791,0.0002675316,0.0001843512,0.00002884869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001121807,0.0002802665,0.0001787998,0.000006139951,0.0001300592,0.00001705211,0.000456386,0.000004298269,0.9037703,0.00007781434,0.09385146,0.0001055638],"study_design_scores_gemma":[0.005775497,0.001155846,0.002665741,0.00009130321,0.00009423178,0.0007359943,0.0009595571,0.000001435849,0.9421775,0.00004269112,0.04613749,0.000162731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9468669,0.047698,0.00006308544,0.0006718065,0.00415938,0.0003076601,0.00001559532,0.00002883297,0.0001886887],"genre_scores_gemma":[0.996705,0.0002119908,0.00007769963,0.0002418478,0.0007428117,0.000003353761,0.00005952328,0.00002665105,0.001931146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04983803,"threshold_uncertainty_score":0.6367549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01065519061887264,"score_gpt":0.2348314463343701,"score_spread":0.2241762557154975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}