{"id":"W2023706819","doi":"10.1006/excr.2000.4952","title":"Rapid Up-Regulation of Peptide Elongation Factor EF-1α Protein Levels Is an Immediate Early Event during Oxidative Stress-Induced Apoptosis","year":2000,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Institute on Aging","keywords":"Biology; Oxidative stress; Apoptosis; Elongation; Cell biology; Elongation factor; Peptide; Event (particle physics); Oxidative phosphorylation; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003130847,0.000450096,0.0005601811,0.0005267659,0.0003609532,0.0004273049,0.0002074514,0.000450275,0.001072227],"category_scores_gemma":[0.000314047,0.0002610312,0.0003892742,0.0003401662,0.0002862036,0.0005982011,0.0003128881,0.0009775795,0.0004611674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004171253,"about_ca_system_score_gemma":0.0001252438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002449153,"about_ca_topic_score_gemma":0.0003015438,"domain_scores_codex":[0.9997749,0.00001904319,0.00001738196,0.00004414358,0.00005839664,0.00008613583],"domain_scores_gemma":[0.9996369,0.00006351424,0.0000952017,0.00003892254,0.00006814356,0.00009733617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001393152,0.00003787985,0.000837358,0.00006110564,0.00001241585,0.0002172252,0.00003895254,0.00002433019,0.9957843,0.0001026168,0.00007715273,0.001413386],"study_design_scores_gemma":[0.00006148494,0.0005575843,0.1015807,0.00002367035,0.00003937239,0.001331256,0.0001991808,0.0003999217,0.8933748,0.0003866424,0.002027699,0.00001769682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838275,0.006326895,0.006965547,0.0002138801,0.0001457565,0.00006747452,0.001039076,0.0001462576,0.001267723],"genre_scores_gemma":[0.9915006,0.001949362,0.002694824,0.0001105219,0.00009482226,0.00009738505,0.001563949,0.00001925935,0.001969311],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001072227,"threshold_uncertainty_score":0.003586948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05556342606602837,"score_gpt":0.3561842530316942,"score_spread":0.3006208269656658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}