{"id":"W2023715623","doi":"10.1038/mt.2010.165","title":"Laminin-111: A Potential Therapeutic Agent for Duchenne Muscular Dystrophy","year":2010,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Duchenne muscular dystrophy; Sarcolemma; Dystrophin; Laminin; Extracellular matrix; Myocyte; Transplantation; Skeletal muscle; Muscular dystrophy; ITGA7; Cell biology; Myogenesis; Utrophin; mdx mouse; Regeneration (biology); Biology; Chemistry; Medicine; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001158755,0.0003693068,0.0001949296,0.0003154787,0.0001479748,0.0001682321,0.0001538086,0.0003830919,0.001088095],"category_scores_gemma":[0.00005074227,0.00009112281,0.0001360707,0.0001985602,0.0001642044,0.0001944989,0.0001585936,0.0003516035,0.0002822005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002556576,"about_ca_system_score_gemma":0.0001737836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005461841,"about_ca_topic_score_gemma":0.0006470534,"domain_scores_codex":[0.999954,0.00001424208,0.000003377419,0.000009097232,0.000009006762,0.00001027697],"domain_scores_gemma":[0.9999794,0.000004191669,0.000005492249,0.000001121566,0.000002564824,0.000007156195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003687492,0.0002722738,0.0005141152,0.0009655725,0.00002341719,0.0007323109,0.00005941742,0.000409885,0.9337465,0.0009867805,0.001254343,0.06066675],"study_design_scores_gemma":[0.0002937264,0.005610402,0.007096703,0.0002207039,0.0002492355,0.003965114,0.00007949009,0.00163562,0.8647698,0.0003839828,0.1156556,0.00003956396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6258222,0.3432456,0.01006153,0.002214967,0.0006328173,0.0001982948,0.0002453877,0.0003139257,0.0172653],"genre_scores_gemma":[0.8505996,0.1241299,0.006981417,0.000533128,0.0001590278,0.000120453,0.0003779283,0.00002480478,0.01707383],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001088095,"threshold_uncertainty_score":0.003639996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007057819747848449,"score_gpt":0.2454396835114751,"score_spread":0.2383818637636267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}