{"id":"W2023715623","doi":"10.1038/mt.2010.165","title":"Laminin-111: A Potential Therapeutic Agent for Duchenne Muscular Dystrophy","year":2010,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Duchenne muscular dystrophy; Sarcolemma; Dystrophin; Laminin; Extracellular matrix; Myocyte; Transplantation; Skeletal muscle; Muscular dystrophy; ITGA7; Cell biology; Myogenesis; Utrophin; mdx mouse; Regeneration (biology); Biology; Chemistry; Medicine; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001517598,0.0002520494,0.0001859624,0.00004518585,0.0001383688,0.00002932648,0.0003121477,0.0002748216,0.00008062469],"category_scores_gemma":[0.00002432837,0.0002306698,0.0003185483,0.00006782877,0.0001403231,0.000003984134,0.00004721664,0.0001617086,0.00001883279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004251061,"about_ca_system_score_gemma":0.0000583964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000978098,"about_ca_topic_score_gemma":0.00000689817,"domain_scores_codex":[0.9987405,0.00007056009,0.0001850976,0.0004964608,0.0001199055,0.0003874905],"domain_scores_gemma":[0.9991342,0.000008582963,0.00007211792,0.0006061325,0.00009590732,0.0000830357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006391883,0.0001607286,0.00005435428,0.000008730282,0.000200562,0.000006729779,0.0000264181,0.00007804835,0.9831486,0.0008159411,0.000273619,0.01458706],"study_design_scores_gemma":[0.004139004,0.001499291,0.002791076,0.000003832181,0.00004791841,0.00001986248,0.0000435894,0.000193062,0.7802088,0.003137609,0.2073456,0.0005703283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9710994,0.001485382,0.02571339,0.0003846138,0.0005059233,0.0005151182,0.00001876148,0.0000299771,0.0002474287],"genre_scores_gemma":[0.9951644,0.0001954871,0.001377209,0.002319437,0.0002758933,0.0001893079,0.0002096059,0.00005837901,0.0002102668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.207072,"threshold_uncertainty_score":0.9406441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007057819747848449,"score_gpt":0.2454396835114751,"score_spread":0.2383818637636267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}