{"id":"W2023737057","doi":"10.1155/2008/512196","title":"Staphylococcal Toxic Shock Syndrome Toxin‐1 Induces the Translocation and Secretion of High Mobility Group‐1 Protein from Both Activated T Cells and Monocytes","year":2008,"lang":"en","type":"article","venue":"Mediators of Inflammation","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Vancouver Hospital and Health Sciences Centre; Providence Health Care","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Superantigen; Peripheral blood mononuclear cell; Secretion; Chromosomal translocation; Toxic shock syndrome; Monocyte; Sepsis; Toxin; Biology; Immunology; Cell biology; Microbiology; T cell; Staphylococcus aureus; Immune system; In vitro; Bacteria; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002393409,0.00009847684,0.0001338764,0.00005039709,0.00006474684,0.00000590639,0.000087037,0.0001105959,0.000007358235],"category_scores_gemma":[0.0001555335,0.00007890462,0.00001983161,0.0001165622,0.0002182897,0.00002827994,0.00003443719,0.00008182808,3.614416e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001274712,"about_ca_system_score_gemma":0.00004744525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001095584,"about_ca_topic_score_gemma":0.00002302352,"domain_scores_codex":[0.9990949,0.0001230642,0.0002716671,0.000226966,0.0001865972,0.00009678031],"domain_scores_gemma":[0.9993983,0.00004495994,0.000176791,0.0002248821,0.0001136495,0.00004141263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001091443,0.0000271986,0.001118897,0.00005085231,0.00002085903,2.481586e-7,0.0003825505,0.00009433413,0.9938087,0.00004588547,0.000003219373,0.004338088],"study_design_scores_gemma":[0.0003508542,0.0001667532,0.06160976,0.00001718807,0.000005750637,0.000002157581,0.0001224378,0.00008769555,0.9371437,0.0003798741,0.00004261291,0.00007123101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99712,0.0003895629,0.001715638,0.0001412758,0.00002861306,0.0005600504,0.00003270369,0.000007226616,0.00000497648],"genre_scores_gemma":[0.9984747,0.0004837874,0.0007385518,0.000004236127,0.00005515777,0.0000512545,0.0001742212,0.000009161785,0.000008943552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06049086,"threshold_uncertainty_score":0.3217637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009572894142465897,"score_gpt":0.2333633848695342,"score_spread":0.2237904907270683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}