{"id":"W2023737057","doi":"10.1155/2008/512196","title":"Staphylococcal Toxic Shock Syndrome Toxin‐1 Induces the Translocation and Secretion of High Mobility Group‐1 Protein from Both Activated T Cells and Monocytes","year":2008,"lang":"en","type":"article","venue":"Mediators of Inflammation","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Vancouver Hospital and Health Sciences Centre; Providence Health Care","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Superantigen; Peripheral blood mononuclear cell; Secretion; Chromosomal translocation; Toxic shock syndrome; Monocyte; Sepsis; Toxin; Biology; Immunology; Cell biology; Microbiology; T cell; Staphylococcus aureus; Immune system; In vitro; Bacteria; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002157907,0.0003998587,0.0002095244,0.0001788558,0.0001014107,0.0002540556,0.00005795753,0.0002009266,0.001261508],"category_scores_gemma":[0.0002028368,0.0001335677,0.0002645302,0.0001490018,0.0001860609,0.0001010201,0.0002623574,0.0004008399,0.0003477646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000213301,"about_ca_system_score_gemma":0.0001975283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003912411,"about_ca_topic_score_gemma":0.0005006173,"domain_scores_codex":[0.9997327,0.00008577186,0.00001906979,0.00002130265,0.00005291488,0.00008831429],"domain_scores_gemma":[0.9998415,0.00004181415,0.00003564194,0.00001971107,0.0000173366,0.00004404038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000467528,0.00005143883,0.0004195563,0.00003686816,0.000004394577,0.0001212586,0.00002592715,0.00004571958,0.9975417,0.00004710331,0.00005867925,0.001179786],"study_design_scores_gemma":[0.0001724471,0.002629584,0.02276051,0.00001701323,0.00002580091,0.0006821763,0.0001653764,0.001294293,0.9698387,0.0001488509,0.002256453,0.000008853597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997837,0.0007031973,0.0006091072,0.00007297643,0.00003085753,0.00001903435,0.0000967512,0.00002319035,0.0006079354],"genre_scores_gemma":[0.9969458,0.0005296074,0.0005087844,0.00008286666,0.00001881886,0.00003354421,0.000288886,0.000005618345,0.001586154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001261508,"threshold_uncertainty_score":0.004220128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009572894142465897,"score_gpt":0.2333633848695342,"score_spread":0.2237904907270683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}