{"id":"W2023815745","doi":"10.1021/jo0110956","title":"Synthesis of a Potent Antagonist of E-Selectin","year":2002,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Anomer; Antagonist; Stereochemistry; Ether; Leaving group; Alpha (finance); Glycosylation; Linkage (software); Combinatorial chemistry; Catalysis; Biochemistry; Organic chemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004233093,0.0002080144,0.0005344168,0.00002210612,0.00006806455,0.00001143231,0.0007176609,0.000165954,0.01055296],"category_scores_gemma":[0.0007371067,0.0001531513,0.0002968658,0.0002381159,0.0002180528,0.00005281563,0.00007746621,0.0003972042,0.000005578891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000927818,"about_ca_system_score_gemma":0.00008056782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007091485,"about_ca_topic_score_gemma":5.672269e-7,"domain_scores_codex":[0.9982669,0.00002639464,0.0009056436,0.000122821,0.0004526551,0.0002255947],"domain_scores_gemma":[0.9974526,0.000524421,0.001147034,0.0005180873,0.0002496448,0.0001082403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001007271,0.0002324947,0.0002223482,0.0004759152,0.0002095336,0.00001635699,0.0002766757,0.000008373127,0.9962214,8.193348e-7,0.0006159058,0.001619477],"study_design_scores_gemma":[0.0003130199,0.00001372702,0.00002594007,0.0002354061,0.000303346,0.0007417975,0.0007923188,0.00004693769,0.9969706,0.00003423115,0.0003814231,0.0001412634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9695991,0.001032917,0.00001881662,0.0003376808,0.00003625231,0.00001821689,0.00002408364,0.00001170514,0.02892124],"genre_scores_gemma":[0.9979465,0.0005709342,0.00007847552,0.000009813173,0.0002243027,8.492527e-7,8.652739e-7,0.00002990493,0.001138382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02834739,"threshold_uncertainty_score":0.9903516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01195075162884596,"score_gpt":0.1965715981117207,"score_spread":0.1846208464828748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}