{"id":"W2023815770","doi":"10.1021/bi200774w","title":"Posttranslational Modifications of the Photoreceptor-Specific ABC Transporter ABCA4","year":2011,"lang":"en","type":"article","venue":"Biochemistry","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Eye Institute","keywords":"Phosphorylation; ABCA4; Biology; ATP-binding cassette transporter; Biochemistry; Serine; Mutant; Transmembrane domain; Dephosphorylation; Cell biology; Molecular biology; Phosphatase; Transporter; Amino acid; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005063303,0.0001044225,0.00006852281,0.00001111696,0.00005844955,0.000004035328,0.0002467639,0.0001128485,0.0002561317],"category_scores_gemma":[0.000007357311,0.00008323312,0.0001135617,0.00007653951,0.0001472771,0.000002092033,0.00001844048,0.00005048304,0.000006565083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005276891,"about_ca_system_score_gemma":0.0000778273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005989567,"about_ca_topic_score_gemma":0.000001661004,"domain_scores_codex":[0.9993623,0.000009710423,0.0001847093,0.0002028744,0.0001219654,0.000118367],"domain_scores_gemma":[0.9995257,0.000002913063,0.00006784784,0.0002978001,0.000066458,0.00003926027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005394328,0.00006679687,0.01122318,0.00001500695,0.00002306646,1.575284e-7,0.0001190821,9.108065e-7,0.9855236,0.00009978447,0.002572783,0.0003016235],"study_design_scores_gemma":[0.000208878,0.00001443381,0.04308502,0.000008789576,0.000008006837,0.000002765146,0.00006216262,0.000002259832,0.9464939,0.00009292655,0.009905881,0.0001149837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9746453,0.0005307615,0.0003943713,0.00008277147,0.00009843673,0.0001043672,0.000040381,0.000007478978,0.02409611],"genre_scores_gemma":[0.997715,0.00008506738,0.0008480237,0.00005270488,0.00005186345,0.00001550344,0.0001337378,0.00001106236,0.001087016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03902977,"threshold_uncertainty_score":0.3394148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0215430110026036,"score_gpt":0.2056304450719481,"score_spread":0.1840874340693445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}