{"id":"W2023815770","doi":"10.1021/bi200774w","title":"Posttranslational Modifications of the Photoreceptor-Specific ABC Transporter ABCA4","year":2011,"lang":"en","type":"article","venue":"Biochemistry","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Eye Institute","keywords":"Phosphorylation; ABCA4; Biology; ATP-binding cassette transporter; Biochemistry; Serine; Mutant; Transmembrane domain; Dephosphorylation; Cell biology; Molecular biology; Phosphatase; Transporter; Amino acid; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009793182,0.0003037798,0.000189672,0.0001455321,0.0001513904,0.0002656246,0.0001270107,0.0002093057,0.0004623979],"category_scores_gemma":[0.0001450083,0.0001137458,0.0002624447,0.000137725,0.0001847164,0.0002091854,0.0001798451,0.0002890597,0.0001981268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002743479,"about_ca_system_score_gemma":0.0001764077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000874072,"about_ca_topic_score_gemma":0.0009833238,"domain_scores_codex":[0.9998885,0.00001986278,0.00001023694,0.0000282688,0.00003091283,0.00002223185],"domain_scores_gemma":[0.9998925,0.00001516567,0.00004082051,0.00001362692,0.00002043568,0.00001760436],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004000249,0.000004320051,0.0004748339,0.0000199526,0.000005690814,0.0000500003,0.00001044663,0.00002337528,0.9988106,0.00003829104,0.000008764626,0.0005136728],"study_design_scores_gemma":[0.000007516472,0.00008781836,0.03009169,0.000004950188,0.00002652895,0.0006301008,0.00004937819,0.0005415282,0.9665422,0.00007176137,0.001938455,0.000008109167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968309,0.00133213,0.001142402,0.00005446234,0.00001180785,0.000008383768,0.0001538034,0.00002442261,0.0004416495],"genre_scores_gemma":[0.996628,0.0007223332,0.001327403,0.00004509563,0.000006307507,0.000009945289,0.0003510936,0.00001170586,0.0008980581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000874072,"threshold_uncertainty_score":0.001990497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0215430110026036,"score_gpt":0.2056304450719481,"score_spread":0.1840874340693445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}