{"id":"W2023821657","doi":"10.1371/journal.pone.0017578","title":"Cytoplasmic Skp2 Expression Is Increased in Human Melanoma and Correlated with Patient Survival","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Coastal Health; University of British Columbia; Vancouver Coastal Health Research Institute","funders":"CIHR Skin Research Training Centre; Canadian Institutes of Health Research; Michael Smith Health Research BC; Canadian Dermatology Foundation","keywords":"Melanoma; SKP2; Tissue microarray; Immunohistochemistry; Cancer research; Medicine; Cancer; Biomarker; Cell cycle; Pathology; Metastasis; Clinical significance; Oncology; Biology; Internal medicine; Ubiquitin; Gene; Ubiquitin ligase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000558799,0.0001217035,0.0001505319,0.00003985353,0.00004888594,0.000006854572,0.00007096089,0.0001172649,0.00006258071],"category_scores_gemma":[0.00001339878,0.0001016237,0.00001612113,0.00004445036,0.0000441498,0.000003534003,0.00007156496,0.00007940815,0.000006680788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006494613,"about_ca_system_score_gemma":0.00002123246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00013436,"about_ca_topic_score_gemma":0.0000861548,"domain_scores_codex":[0.9992658,0.00005049082,0.0001397366,0.0002651242,0.0001140551,0.0001648219],"domain_scores_gemma":[0.9996019,0.000005368244,0.00005784991,0.0002205532,0.00003457244,0.00007973766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002156502,0.0004998607,0.1163244,0.00002187164,0.00004080373,0.00001823309,0.0003180107,1.171607e-7,0.8823929,0.00002071463,0.00006543114,0.00008200396],"study_design_scores_gemma":[0.0009885586,0.001032144,0.02801397,0.00009333044,0.00002605877,0.00000510029,0.00007319413,0.00001973817,0.9694642,0.00003420049,0.00008668487,0.0001627761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954411,0.0001355915,0.00001802178,0.000006499786,0.00001678599,0.0001803082,0.00001578781,0.00001183975,0.004174042],"genre_scores_gemma":[0.9990183,0.0000354528,0.0005948425,0.00007271827,0.00002506952,0.00002357308,0.00007774712,0.00001752736,0.0001348057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08831041,"threshold_uncertainty_score":0.4144094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02843053325261224,"score_gpt":0.1897545457911378,"score_spread":0.1613240125385256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}