{"id":"W2023853884","doi":"10.1093/nar/gkt527","title":"Binding of RNA by APOBEC3G controls deamination-independent restriction of retroviruses","year":2013,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"APOBEC3G; Biology; RNA; Deamination; Infectivity; Cytidine deaminase; DNA; Molecular biology; Biochemistry; Genetics; Virology; Virus; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0009447599,0.0001228125,0.0002912546,0.0004666382,0.0002160728,0.00002353605,0.0003552267,0.000236666,0.002603788],"category_scores_gemma":[0.0006291809,0.0001008705,0.00008639752,0.0004584085,0.0004789472,0.0001777083,0.0001497045,0.0004961655,0.00246799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001598001,"about_ca_system_score_gemma":0.0001375911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001886616,"about_ca_topic_score_gemma":0.00001805061,"domain_scores_codex":[0.9978113,0.0006013018,0.0003841287,0.0002816144,0.0003389316,0.000582767],"domain_scores_gemma":[0.9982371,0.0005962293,0.000116178,0.0003676172,0.0006190441,0.00006377652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001408175,0.0003432196,0.02278541,0.00003473458,0.0001821451,0.000002587153,0.0001424491,7.812463e-7,0.9378524,0.0005442946,0.02349518,0.01447601],"study_design_scores_gemma":[0.003371898,0.001754223,0.06762831,0.00006833885,0.00002089603,0.00000818112,0.0009933654,0.00001500116,0.9141654,0.0003948864,0.0114282,0.0001512695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916992,0.001118103,0.0000603277,0.0002622238,0.00008401237,0.0006909956,0.00017302,0.00002438664,0.005887797],"genre_scores_gemma":[0.9949763,0.0004391171,0.00006851456,0.000006205139,0.00001471625,0.0001087073,0.0001410224,0.00001758841,0.004227797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04484289,"threshold_uncertainty_score":0.9983087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03204711975361923,"score_gpt":0.3190788130359122,"score_spread":0.287031693282293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}