{"id":"W2023888949","doi":"10.1074/jbc.m114.562603","title":"Identification of the Flagellin Glycosylation System in Burkholderia cenocepacia and the Contribution of Glycosylated Flagellin to Evasion of Human Innate Immune Responses","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Cystic Fibrosis Trust","keywords":"Flagellin; TLR5; Burkholderia cenocepacia; Microbiology; Biology; Glycan; Gene cluster; Glycosylation; Burkholderia; Immune system; Innate immune system; Toll-like receptor; Molecular biology; Gene; Immunology; Bacteria; Biochemistry; Genetics; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001465792,0.0002017076,0.0001036036,0.0001450032,0.00007846265,0.0001435477,0.0000684775,0.0001931668,0.0002359517],"category_scores_gemma":[0.000167898,0.00007750698,0.0001508927,0.0001298103,0.0000958681,0.00009700194,0.0001323107,0.0002166981,0.00007412238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001609867,"about_ca_system_score_gemma":0.0001349073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001296556,"about_ca_topic_score_gemma":0.001186133,"domain_scores_codex":[0.9999201,0.00002012369,0.000007884512,0.00001241823,0.00001882259,0.00002062348],"domain_scores_gemma":[0.9999303,0.00001034779,0.00002024105,0.000008148076,0.00001230354,0.0000187411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008137868,0.00001321654,0.001972684,0.00001737123,0.000003770125,0.00004608234,0.00001288743,0.00003782447,0.9967057,0.00002193472,0.000006951244,0.001080104],"study_design_scores_gemma":[0.000021737,0.0007538915,0.1385221,0.00001898268,0.000048483,0.001107181,0.0001609587,0.001785649,0.8554753,0.0001040874,0.001990504,0.00001112785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980186,0.0008371074,0.0008384648,0.00004748897,0.000004434281,0.00001084132,0.0001246844,0.000005332451,0.0001130297],"genre_scores_gemma":[0.9973242,0.0004623866,0.001478949,0.00003848284,0.000004415937,0.000008113876,0.0003981013,0.000002045437,0.0002833233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001296556,"threshold_uncertainty_score":0.00257808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01630424743572412,"score_gpt":0.2956958516822307,"score_spread":0.2793916042465066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}