{"id":"W2023984097","doi":"10.1016/j.ccr.2007.10.003","title":"Bmi1 and Cell of Origin Determinants of Brain Tumor Phenotype","year":2007,"lang":"en","type":"letter","venue":"Cancer Cell","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"BMI1; Biology; Neural stem cell; Phenotype; Cancer research; Cancer stem cell; Precursor cell; Stem cell; Cell; Lineage (genetic); Brain tumor; Regulator; Pathology; Genetics; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007255214,0.0003985292,0.0009718863,0.0003406979,0.0008677916,0.001290321,0.0006635088,0.01033553,0.004983177],"category_scores_gemma":[0.003178313,0.0003110325,0.0004600495,0.0002128013,0.001220576,0.0009526454,0.0006255541,0.0120015,0.00176866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001301133,"about_ca_system_score_gemma":0.0006217266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008434826,"about_ca_topic_score_gemma":0.001516424,"domain_scores_codex":[0.999586,0.0001373923,0.00003857438,0.00004884231,0.000105861,0.00008332424],"domain_scores_gemma":[0.9989676,0.0006961202,0.00005264113,0.00005337753,0.0001159756,0.0001141902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009634889,0.0001667856,0.002443195,0.0001783576,0.00005117209,0.01116516,0.0002022408,0.0003097696,0.006788748,0.01898558,0.9162032,0.0425422],"study_design_scores_gemma":[0.0008980569,0.0004699701,0.008576424,0.0002152526,0.0001596814,0.01977186,0.0007318697,0.003877697,0.01277653,0.0377185,0.9146755,0.0001286651],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.0113984,0.006557201,0.0007101711,0.9518901,0.01781842,0.00002940917,0.0001613356,0.00007883592,0.01135612],"genre_scores_gemma":[0.1982082,0.01627013,0.002314789,0.6336884,0.1003015,0.0002913354,0.0003533004,0.0001178239,0.04845456],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01033553,"threshold_uncertainty_score":0.01667041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02679227667900691,"score_gpt":0.3044451791462515,"score_spread":0.2776529024672446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}