{"id":"W2023991830","doi":"10.1371/journal.pone.0001868","title":"FAK/src-Family Dependent Activation of the Ste20-Like Kinase SLK Is Required for Microtubule-Dependent Focal Adhesion Turnover and Cell Migration","year":2008,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Focal adhesion; Paxillin; Cell biology; Proto-oncogene tyrosine-protein kinase Src; Cell migration; Cytoskeleton; Microtubule; PTK2; Cell adhesion; Kinase; Biology; Signal transduction; Chemistry; Protein kinase A; Cell; Mitogen-activated protein kinase kinase; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008110075,0.0001172108,0.0001240757,0.00003116358,0.0001314917,0.00001298777,0.0001024401,0.00012976,0.00001361332],"category_scores_gemma":[0.00003654121,0.00009840228,0.00008562335,0.00004407526,0.00002666745,0.00001122322,0.00008108254,0.00007534489,0.000002635049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002362591,"about_ca_system_score_gemma":0.0000455768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005678692,"about_ca_topic_score_gemma":0.00004876578,"domain_scores_codex":[0.9991733,0.00003277267,0.0002102519,0.0002596914,0.0001925507,0.0001314127],"domain_scores_gemma":[0.9993704,0.00001541825,0.0001414805,0.0002818186,0.0001491226,0.00004176948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001398085,0.0005014386,0.0003724261,0.00004759974,0.00005472397,3.667049e-7,0.00009978796,0.00000396122,0.9978355,0.00001316594,0.0008038369,0.0001273428],"study_design_scores_gemma":[0.0006756391,0.0003323763,0.0006617651,0.00004454828,0.00006012887,0.000003679838,0.00007544042,0.0006464042,0.9957372,0.00003643679,0.001612215,0.0001141927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966532,0.0003298909,0.002063293,0.0002119971,0.00009066114,0.0004851943,0.00005595169,0.000005770975,0.0001040134],"genre_scores_gemma":[0.9969856,0.0003491313,0.0005189583,0.0002531653,0.00009281235,0.00004297808,0.00008975306,0.00002004335,0.001647611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002098368,"threshold_uncertainty_score":0.4012729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03028975328939189,"score_gpt":0.2188784247402148,"score_spread":0.1885886714508229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}