{"id":"W2023991830","doi":"10.1371/journal.pone.0001868","title":"FAK/src-Family Dependent Activation of the Ste20-Like Kinase SLK Is Required for Microtubule-Dependent Focal Adhesion Turnover and Cell Migration","year":2008,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Focal adhesion; Paxillin; Cell biology; Proto-oncogene tyrosine-protein kinase Src; Cell migration; Cytoskeleton; Microtubule; PTK2; Cell adhesion; Kinase; Biology; Signal transduction; Chemistry; Protein kinase A; Cell; Mitogen-activated protein kinase kinase; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009865691,0.0002927185,0.0001896105,0.0001732976,0.000218229,0.0002644077,0.0001322054,0.000188986,0.001360924],"category_scores_gemma":[0.0001500267,0.0001726902,0.0002163756,0.00009282406,0.0002028987,0.0002083162,0.0002990228,0.0002501689,0.0007126565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003862565,"about_ca_system_score_gemma":0.0002162564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003560151,"about_ca_topic_score_gemma":0.0007192622,"domain_scores_codex":[0.9998977,0.00001460758,0.00001110844,0.0000193703,0.00002739546,0.00002982523],"domain_scores_gemma":[0.9998683,0.00001554769,0.00004970462,0.0000136729,0.00001231581,0.00004049136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006693222,0.000007803434,0.0002122706,0.00001570189,0.000001600972,0.00006450813,0.000004525495,0.00003744705,0.9990836,0.0000867198,0.00002218643,0.0003966015],"study_design_scores_gemma":[0.00001728922,0.00007869789,0.01492265,0.000003954784,0.000007646798,0.0007065495,0.00002672917,0.001963362,0.9808077,0.00009150252,0.00136913,0.000004847735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972448,0.000474374,0.001327375,0.00005456971,0.000006890246,0.000004848425,0.0001239778,0.00003519302,0.0007279675],"genre_scores_gemma":[0.9981412,0.0001494166,0.0005529393,0.00001437492,0.000003063106,0.00000815862,0.0002600815,0.00001227312,0.000858528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001360924,"threshold_uncertainty_score":0.004552722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03028975328939189,"score_gpt":0.2188784247402148,"score_spread":0.1885886714508229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}