{"id":"W2024062615","doi":"10.1055/s-0029-1242459","title":"Inherited Colorectal Cancer Syndromes","year":2009,"lang":"en","type":"article","venue":"Clinics in Colon and Rectal Surgery","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Medicine; Colorectal cancer; Familial adenomatous polyposis; Malignancy; Genetic testing; Genetic predisposition; Lynch syndrome; Cancer; Cowden syndrome; Genetic counseling; Peutz–Jeghers syndrome; Internal medicine; Disease; Oncology; Germline mutation; Genetics; Mutation; DNA mismatch repair; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005135264,0.0002101183,0.0006327352,0.0002195595,0.00006065322,0.00002257532,0.00006382274,0.0003087359,0.0002857232],"category_scores_gemma":[0.0005643026,0.0001876034,0.0001466395,0.0004966646,0.0001569737,0.0000494401,0.00003983184,0.0004392279,0.00001092981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001525793,"about_ca_system_score_gemma":0.0003055151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006064675,"about_ca_topic_score_gemma":0.0001374623,"domain_scores_codex":[0.9983602,0.00008248397,0.0005258804,0.0004173032,0.0002337183,0.0003804736],"domain_scores_gemma":[0.998705,0.0007499435,0.0001121543,0.0001589175,0.00007646864,0.0001974601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001571634,0.0003976623,0.7740574,0.00008799457,0.00005818745,0.0003529727,0.0002829423,0.000008274983,0.007789881,0.00002866984,0.004368534,0.2109958],"study_design_scores_gemma":[0.0009350895,0.0007922761,0.9861587,0.00032288,0.00004445731,0.0002149423,0.00006541603,0.0003129495,0.00296807,0.0004185912,0.007452664,0.0003139777],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991499,0.00322756,0.000001733695,0.001416771,0.001484229,0.000371088,0.000009580377,0.00008168261,0.00190836],"genre_scores_gemma":[0.9939598,0.003852351,0.0001672802,0.001329965,0.0001680472,0.00004399542,0.00001210576,0.00002239532,0.0004440396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2121012,"threshold_uncertainty_score":0.7650244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04753596812903142,"score_gpt":0.348451409330926,"score_spread":0.3009154412018946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}