{"id":"W2024103813","doi":"10.1038/nsmb1189","title":"An arginine ladder in OprP mediates phosphate-specific transfer across the outer membrane","year":2006,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Periplasmic space; Bacterial outer membrane; Arginine; Chemistry; Extracellular; Biophysics; Membrane; Phosphate; Lysine; Biochemistry; Cell biology; Crystallography; Biology; Amino acid; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002018858,0.0003705166,0.0003131406,0.00004521682,0.0001403226,0.00006645532,0.000421194,0.0009604868,0.00005856772],"category_scores_gemma":[0.00002099681,0.0002466816,0.0001565539,0.0001848939,0.0002922815,0.0000106903,0.00008215239,0.0005619298,0.000004994071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001604729,"about_ca_system_score_gemma":0.00003082036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001372343,"about_ca_topic_score_gemma":0.0003891182,"domain_scores_codex":[0.9979609,0.0001946375,0.0003633993,0.0006930712,0.0001218927,0.0006660951],"domain_scores_gemma":[0.999211,0.00001465042,0.0000609938,0.0005443814,0.00009148261,0.00007755734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000189549,0.00001734356,0.001132543,0.000005071586,0.00003192759,0.00003338031,0.00005125598,0.00006557604,0.9945084,0.0021108,0.0001594069,0.001694718],"study_design_scores_gemma":[0.001052496,0.0002081165,0.01776764,0.00000675012,0.00001267125,0.00007953944,0.00004628651,0.00003320249,0.9573575,0.0003840754,0.02266013,0.0003916036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929553,0.004326239,0.0001544738,0.001145409,0.0008572317,0.0002865664,0.0001178742,0.00002596956,0.0001309427],"genre_scores_gemma":[0.9956947,0.0001029749,0.0005078292,0.001523115,0.0007235879,0.00001050316,0.001346331,0.00004336127,0.00004760872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03715094,"threshold_uncertainty_score":0.9999986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003613224328139136,"score_gpt":0.2622466600599433,"score_spread":0.2586334357318041,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}