{"id":"W2024104987","doi":"10.1126/science.1074360","title":"Cytoprotective Role of Ca <sup>2+</sup> - Activated K <sup>+</sup> Channels in the Cardiac Inner Mitochondrial Membrane","year":2002,"lang":"en","type":"article","venue":"Science","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":477,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute","keywords":"Inner mitochondrial membrane; Mitochondrial apoptosis-induced channel; Membrane potential; Mitochondrion; Cell biology; Chemistry; Myocyte; Potassium channel; Biophysics; Inner membrane; Adenosine triphosphate; Cell; Membrane; Ion channel; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000790337,0.0002235017,0.000483897,0.0003062093,0.0002284509,0.00004237755,0.0004021357,0.000164324,0.0001913499],"category_scores_gemma":[0.0005495166,0.0001427654,0.0002186217,0.001922505,0.0006986887,0.0002771848,0.0001440685,0.0004896192,0.00006329246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001574782,"about_ca_system_score_gemma":0.0001837078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004026231,"about_ca_topic_score_gemma":0.000001407934,"domain_scores_codex":[0.9973359,0.0001326433,0.0003266654,0.0005765414,0.001090767,0.000537521],"domain_scores_gemma":[0.9987261,0.0001308899,0.00009309025,0.0006729917,0.0002284067,0.000148545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001352616,0.0001614701,0.0004184283,0.00003334813,0.00002322813,0.00002172592,0.01933012,0.003576503,0.9730127,0.00003330321,0.000577783,0.002676123],"study_design_scores_gemma":[0.001457395,0.0002614159,0.0005980567,0.0001704405,0.00006285111,0.0000714058,0.005780535,0.02571027,0.9593112,0.00005822257,0.006280589,0.0002376219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889846,0.0003509719,0.000008570389,0.0009557631,0.0002751477,0.0009727008,0.00001647737,0.000034945,0.008400788],"genre_scores_gemma":[0.9983348,0.00006919594,0.0001494991,0.0001935172,0.0005417565,0.00007167256,0.000005650437,0.00001701249,0.0006168681],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02213377,"threshold_uncertainty_score":0.5821804,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01068980400210939,"score_gpt":0.2387836083402865,"score_spread":0.2280938043381771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}