{"id":"W2024148072","doi":"10.1038/sj.cgt.7700466","title":"Intratumoral coinjection of two adenoviral vectors expressing functional interleukin-18 and inducible protein-10, respectively, synergizes to facilitate regression of established tumors","year":2002,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Cancer research; CD8; Cytotoxic T cell; Immunotherapy; Cytokine; Genetic enhancement; Tumor necrosis factor alpha; Viral vector; Tumor microenvironment; Chemokine; Biology; T cell; Interleukin 2; Immune system; Immunology; Recombinant DNA; Gene; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004563353,0.0009571434,0.0005674882,0.0009274026,0.0001859759,0.0005321091,0.000293162,0.0005350995,0.001698991],"category_scores_gemma":[0.0001708282,0.0002686967,0.0004885203,0.0004119802,0.0004733072,0.0003443561,0.0003180414,0.001419761,0.0005697031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003618256,"about_ca_system_score_gemma":0.0004678067,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004802407,"about_ca_topic_score_gemma":0.0009414465,"domain_scores_codex":[0.9993986,0.00009322198,0.00002985729,0.00009847171,0.00016688,0.0002128409],"domain_scores_gemma":[0.9996388,0.0001072884,0.00007936017,0.00004815917,0.00001171927,0.0001146476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006441872,0.0004639039,0.0001663986,0.00003665143,0.00001479822,0.00008789561,0.00001901083,0.000155182,0.9944656,0.0003861183,0.0001589656,0.003401184],"study_design_scores_gemma":[0.0001061944,0.002060334,0.001208952,0.000005633498,0.00004259045,0.0003282229,0.00001683684,0.001276382,0.9927183,0.0000686791,0.002161206,0.00000658428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840173,0.002458926,0.005644757,0.0002845589,0.0003855054,0.0001498273,0.0002570998,0.0004483786,0.006353735],"genre_scores_gemma":[0.9906451,0.001008505,0.003374093,0.00006657258,0.00007019058,0.00007040491,0.0002646637,0.0000333756,0.004467284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001698991,"threshold_uncertainty_score":0.00568372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07241367648858245,"score_gpt":0.2804831563346636,"score_spread":0.2080694798460812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}