{"id":"W2024156402","doi":"10.1002/1096-9861(20000724)423:2<261::aid-cne6>3.0.co;2-6","title":"Chemical characterization of leptin-activated neurons in the rat brain","year":2000,"lang":"en","type":"article","venue":"The Journal of Comparative Neurology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":359,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health","keywords":"Leptin; Nucleus; Hypothalamus; Endocrinology; Internal medicine; Biology; Arcuate nucleus; Arc (geometry); Solitary tract; Galanin; Parabrachial Nucleus; In situ hybridization; Neuropeptide; Lateral parabrachial nucleus; Area postrema; Central nervous system; Leptin receptor; Neuroscience; Messenger RNA; Medicine; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006284088,0.0002982532,0.0002045356,0.0005401251,0.000200657,0.000227651,0.0001709346,0.0001924751,0.001006253],"category_scores_gemma":[0.0000798858,0.0001471538,0.0002163199,0.0002691417,0.000173252,0.0002859145,0.0001460134,0.0003877897,0.0002905285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001665017,"about_ca_system_score_gemma":0.000271844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009953722,"about_ca_topic_score_gemma":0.001799465,"domain_scores_codex":[0.9999543,0.000002574199,0.00000434941,0.00001052837,0.00001310907,0.00001513252],"domain_scores_gemma":[0.9999435,0.000005500595,0.00001199494,0.000003691693,0.00001465237,0.00002065799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007865721,0.00001561149,0.0004142975,0.00005351896,0.000005562796,0.0001011438,0.00001682312,0.000011706,0.9975364,0.00004986803,0.00001017138,0.001706279],"study_design_scores_gemma":[0.00007055755,0.001861532,0.0923506,0.00005819647,0.000118676,0.002974022,0.0003475053,0.0007550229,0.896509,0.0003377641,0.00459362,0.00002353328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841261,0.008683444,0.003811104,0.00008933929,0.00004255874,0.00006465458,0.0007589922,0.00005270299,0.002371142],"genre_scores_gemma":[0.9638254,0.01319194,0.01203509,0.0001333745,0.0000590216,0.0002928042,0.002468206,0.00003735454,0.007956713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001006253,"threshold_uncertainty_score":0.003366232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03941402901242166,"score_gpt":0.2928108615996823,"score_spread":0.2533968325872606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}