{"id":"W2024160187","doi":"10.3109/13816810.2011.620056","title":"Choroideremia: A review of general findings and pathogenesis","year":2011,"lang":"en","type":"review","venue":"Ophthalmic Genetics","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Choroideremia; Retinal pigment epithelium; Pathogenesis; Rab; Dystrophy; Biology; Retinal degeneration; Retinal; Genetics; Medicine; Gene; Pathology; Ophthalmology; GTPase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002217665,0.0004466833,0.001052366,0.00008029757,0.00004098759,0.00001083472,0.0003489461,0.0004364651,0.00007201691],"category_scores_gemma":[0.00007073877,0.0003911617,0.0003539474,0.0001491827,0.0001075586,0.0000014972,0.0002811584,0.0001287682,0.00001463424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001146086,"about_ca_system_score_gemma":0.0002736482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005487047,"about_ca_topic_score_gemma":0.00000100487,"domain_scores_codex":[0.9982663,0.0001081593,0.0006637092,0.0005397397,0.0001415727,0.0002805269],"domain_scores_gemma":[0.9989821,0.00001213024,0.0003084792,0.0004944042,0.00009164947,0.0001112218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007762826,0.00004793524,0.0002352223,0.1265781,0.0002239006,0.00001089893,0.00001376226,7.204097e-8,0.0007080475,0.00002626129,0.004439831,0.8677083],"study_design_scores_gemma":[0.0001141124,0.0001325207,0.0001008788,0.01628647,0.0005035886,0.0002821221,0.000003817376,2.291036e-7,0.0003006077,0.00002019634,0.9817996,0.0004558488],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001535919,0.9949723,0.0000111669,0.000004948663,0.0001301979,0.0005423772,0.00004966309,0.000005054555,0.002748365],"genre_scores_gemma":[0.00002294194,0.9960653,0.001858849,0.00007154306,0.00009466963,0.00006284917,0.0003981928,0.00007009946,0.001355568],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9773598,"threshold_uncertainty_score":0.999854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02964899800851533,"score_gpt":0.3008469819483632,"score_spread":0.2711979839398478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}